Osteoarthritis (OA) is a type of joint disease associated with wear and tear, inflammation,
and aging. Mechanical stress along with synovial inflammation promotes the degradation of …

Nuclear factor-kappaB (NF-κB) proteins constitute a family of transcription factors that are
stimulated by pro-inflammatory cytokines, chemokines, stress-related factors and …

In the context of OA disease, NF-κB transcription factors can be triggered by a host of stress-
related stimuli including pro-inflammatory cytokines, excessive mechanical stress and ECM …

The nuclear factor-κB (NF-κB) is a transcription factor that regulates the expression of genes
that control cell proliferation and apoptosis, as well as genes that respond to inflammation …

Osteoarthritis (OA), a whole-joint disease driven by abnormal biomechanics and attendant
cell-derived and tissue-derived factors, is a rheumatic disease with the highest prevalence …

The family of nuclear factor-kappaB (NF-κB) transcription factors is intimately involved in the
regulation of expression of numerous genes in the setting of the inflammatory response …

The nuclear factor-κB (NF-κB) signaling pathway regulates multiple processes in innate and
adaptive immune cells. This pathway is involved in inflammation through the regulation of …

Human cells have to deal with the constant production of reactive oxygen species (ROS).
Although ROS overproduction might be harmful to cell biology, there are plenty of data …

The transcription factor NF-κB has been well recognized as a pivotal regulator of
inflammation in rheumatoid arthritis (RA), but recent developments revealed a broad …

Inflammation is a defensive mechanism for pathogen clearance and maintaining tissue
homeostasis. In the skeletal system, inflammation is closely associated with many bone …