Glomerular Filtration and Albuminuria Chronic kidney diseases generally arise from a
disordered kidney filtration barrier within glomeruli. This review describes the roles of …

The glomerular filtration barrier is a highly specialized blood filtration interface that displays
a high conductance to small and midsized solutes in plasma but retains relative …

A glomerulus is the network of capillaries that resides in the Bowman's capsule that
functions as a filtration unit of kidney. The glomerular function ensures that essential plasma …

A large body of evidence indicates that proteinuria is a strong predictor of morbidity, a cause
of inflammation, oxidative stress and progression of chronic kidney disease, and …

In the past decade, our understanding of the role of podocytes in the function of the
glomerular filtration barrier, and of the role of podocyte injury in the pathogenesis of …

The mechanism of albuminuria is perhaps one of the most complex yet important questions
in renal physiology today. Recent studies have directly demonstrated that the normal …

The essential function of the kidney is to ensure formation of a relatively protein-free ultra-
filtrate, urine. The rate of filtration and composition of the primary renal filtrate is determined …

The key question is not why some patients have proteinuria but rather why not all people
have it. In the present review, we will present an update on the glomerular barrier after the …

Proteinuria is the hallmark of diabetic kidney disease (DKD) and is an independent risk
factor for both renal disease progression, and cardiovascular disease. Although the …

One of the earliest clinically detectable abnormalities in diabetic nephropathy is
microalbuminuria that eventually progresses to proteinuria. The degree of proteinuria …