Curcumin: an inflammasome silencer
Curcumin is the major bioactive polyphenolic ingredient of turmeric. Increasing evidence
indicates that the health benefits of curcumin are mediated through its anti-inflammatory and …
indicates that the health benefits of curcumin are mediated through its anti-inflammatory and …
Curcumin suppresses IL-1β secretion and prevents inflammation through inhibition of the NLRP3 inflammasome
H Yin, Q Guo, X Li, T Tang, C Li, H Wang… - The Journal of …, 2018 - journals.aai.org
Turmeric is traditionally used as a spice and coloring in foods. Curcumin is the primary
active ingredient in the turmeric, and compelling evidence has shown that it has the ability to …
active ingredient in the turmeric, and compelling evidence has shown that it has the ability to …
Curcumin: a modulator of inflammatory signaling pathways in the immune system
KR Kahkhaie, A Mirhosseini, A Aliabadi… - …, 2019 - Springer
Curcumin is a natural compound derived from the spice, turmeric, that has been extensively
reported for its efficacy in controlling or treatment of several inflammatory diseases. There is …
reported for its efficacy in controlling or treatment of several inflammatory diseases. There is …
Curcumin: An effective inhibitor of interleukin-6
M Ghandadi, A Sahebkar - Current pharmaceutical design, 2017 - ingentaconnect.com
Curcumin is apolyphenolic cominflammatory effects of curcumin. Moreover, curcumin can be
considered as potential therapy against IL-6 involvepound found in the dietary spice …
considered as potential therapy against IL-6 involvepound found in the dietary spice …
Curcumin in inflammatory diseases
Curcumin (diferuloylmethane), a yellow coloring agent extracted from turmeric is also used
as a remedy for the treatment and prevention of inflammatory diseases. Acute and chronic …
as a remedy for the treatment and prevention of inflammatory diseases. Acute and chronic …
Curcumin suppresses NLRP3 inflammasome activation and protects against LPS‐induced septic shock
Z Gong, J Zhou, H Li, Y Gao, C Xu… - Molecular nutrition & …, 2015 - Wiley Online Library
Scope The NLRP3 inflammasome responds to various pathogen‐derived factors and
danger‐associated molecules, mediating IL‐1β maturation, therefore is involved in multiple …
danger‐associated molecules, mediating IL‐1β maturation, therefore is involved in multiple …
Curcumin prevents osteoarthritis by inhibiting the activation of inflammasome NLRP3
Y Sun, W Liu, H Zhang, H Li, J Liu, F Zhang… - Journal of Interferon & …, 2017 - liebertpub.com
Curcumin has shown protective potential on osteoarthritis. However, its effect on treatment of
osteoarthritis remains elusive so far. This study aimed to determine whether curcumin could …
osteoarthritis remains elusive so far. This study aimed to determine whether curcumin could …
Anti-inflammatory effects of curcumin in the inflammatory diseases: Status, limitations and countermeasures
Y Peng, M Ao, B Dong, Y Jiang, L Yu… - Drug design …, 2021 - Taylor & Francis
Curcumin is a natural compound with great potential for disease treatment. A large number
of studies have proved that curcumin has a variety of biological activities, among which anti …
of studies have proved that curcumin has a variety of biological activities, among which anti …
Curcumin represses NLRP3 inflammasome activation via TLR4/MyD88/NF-κB and P2X7R signaling in PMA-induced macrophages
F Kong, B Ye, J Cao, X Cai, L Lin, S Huang… - Frontiers in …, 2016 - frontiersin.org
Aims: In the NOD-like receptor (NLR) family, the pyrin domain containing 3 (NLRP3)
inflammasome is closely related to the progression of atherosclerosis. This study aimed to …
inflammasome is closely related to the progression of atherosclerosis. This study aimed to …
Curcumin ameliorates monosodium urate‐induced gouty arthritis through Nod‐like receptor 3 inflammasome mediation via inhibiting nuclear factor‐kappa B signaling
X Li, DQ Xu, DY Sun, T Zhang, X He… - Journal of Cellular …, 2019 - Wiley Online Library
Background Monosodium urate (MSU) crystals‐induced inflammation is a key initiator in
gouty arthritis. Curcumin is an active ingredient possessing anti‐inflammatory efficacy. But …
gouty arthritis. Curcumin is an active ingredient possessing anti‐inflammatory efficacy. But …