Tissue injury evokes highly conserved, tightly regulated inflammatory responses and less
well-understood host repair responses. Both inflammation and repair involve the …

Pulmonary fibrosis and architectural remodeling of tissues can severely disrupt lung
function, often with fatal consequences. The etiology of pulmonary fibrotic diseases is varied …

Idiopathic pulmonary fibrosis is a disease of older adults leading to progressive dyspnea
and reduced exercise capacity, typically resulting in death within 3-5years of diagnosis …

Pulmonary fibrosis is a chronic lung disease characterized by excessive accumulation of
extracellular matrix (ECM) and remodeling of the lung architecture. Idiopathic pulmonary …

The pathogenesis of idiopathic pulmonary fibrosis (IPF) involves a complex interplay of cell
types and signaling pathways. Recurrent alveolar epithelial cell (AEC) injury may occur in …

Pulmonary fibrosis is a highly heterogeneous and lethal pathological process with limited
therapeutic options. Although research on the pathogenesis of pulmonary fibrosis has …

Idiopathic pulmonary fibrosis (IPF) is the most frequent fibrotic diffuse parenchymal lung
disease. Its prognosis is devastating:> 50% of the patients die within 3 years after diagnosis …

Fibrogenesis is an often-deadly process with increasing world-wide incidence and limited
therapeutic options. Pulmonary fibrogenesis involves remodeling of the distal airspace and …

Fibrogenesis involves a dynamic interplay between factors that promote the biosynthesis
and deposition of extracellular matrix along with pathways that degrade the extracellular …

Idiopathic pulmonary fibrosis (IPF) is a chronic fibrotic disease of the lung that is marked by
progressive decline in pulmonary function and ultimately respiratory failure. Genetic and …