Ionizing radiation produces clustered DNA damage that contains two or more lesions in 10–
20 bp. It is believed that the complexity of clustered damage (ie, the number of lesions per …

Clustered DNA damage is related to the biological effects of ionizing radiation. However, its
precise yield and complexity (ie, number of lesions per damaged site) in vivo remain …

Ionizing radiation induces multiple damaged sites (clustered damage) together with isolated
lesions in DNA. Clustered damage consists of closely spaced lesions within a few helical …

Double-strand breaks (DSBs) are the most critical radiation-induced lesions, because they
result in the fragmentation of the DNA molecule and because a single unrepaired DSB may …

Double-stranded pBS plasmid DNA was irradiated with gamma rays at doses ranging from 1
to 12 kGy and electron beams from 1 to 10 kGy. Fragment-size distributions were …

Using atomic force microscopy (AFM), we have investigated neutron-induced DNA double-
strand breaks in plasmids in aqueous solution. AFM permits direct measurement of …

Elsässer, T., Brons, S., Psonka, K., Scholz, M., Gudowska-Nowak, E. and Taucher-Scholz, G.
Biophysical Modeling of Fragment Length Distributions of DNA Plasmids after X and Heavy …

The detection and quantification of ionizing radiation damage to DNA at a single‐molecule
level by atomic force microscopy (AFM) is reported. The DNA damage‐detection technique …

Abstract Pang, D., Rodgers, JE, Berman, BL, Chasovskikh, S. and Dritschilo, A. Spatial
Distribution of Radiation-Induced Double-Strand Breaks in Plasmid DNA as Resolved by …

According to the experimental evidence damage induced by densely ionizing radiation in
chromosomes and DNA molecules is distributed in the form of clusters. The most critical type …