Advances in our understanding of the intricate molecular mechanisms for transformation of a
normal cell to a cancer cell, and the aberrant control of complementary pathways, have …

In the field of oncology, clinical molecular diagnostics and biomarker discoveries are
constantly advancing as the intricate molecular mechanisms that transform a normal cell into …

Cancer is a group of diseases characterized by the uncontrolled growth and spread of
abnormal cells and oncology is a branch of medicine that deals with tumors. The last decade …

Over the last 10 years there has been an explosion of information about the molecular
biology of cancer. A challenge in oncology is to translate this information into advances in …

Many experts agree that personalized cancer medicine, defined here as treatment based on
the molecular characteristics of a tumor from an individual patient, has great potential in the …

The future of drug development in oncology lies in identifying subsets of patients who will
benefit from particular therapies, using predictive biomarkers. These technologies offer hope …

Advances in genomics, proteomics and molecular pathology have generated many
candidate biomarkers with potential clinical value. Their use for cancer staging and …

Physicians need improved tools for selecting treatments for individual patients. Many
diagnostic entities hat were traditionally viewed as individual diseases are heterogeneous in …

This Perspective highlights biomarkers that are expressed as a consequence of cancer
development and progression. We focus on those biomarkers that are most relevant for …

Over the past 20 years, there has been an exponential increase in the number of
biomarkers. At the last count, there were 768,259 papers indexed in PubMed. gov directly …