Marfan syndrome (MFS) is an autosomal dominant, age-related but highly penetrant
condition with substantial intrafamilial and interfamilial variability. MFS is caused by …

Marfan syndrome (MFS) is an autosomal dominant connective tissue disorder involving the
cardiovascular, skeletal and ocular systems, the integument, lungs and dura. Cardinal …

▪ Abstract The Marfan syndrome (MFS), initially described just over 100 years ago, was
among the first conditions classified as a heritable disorder of connective tissue. MFS lies at …

Marfan syndrome (MFS) is an inherited autosomal dominant multisystem disease caused by
mutations in the FBN1 gene encoding fibrillin-1, an extracellular matrix glycoprotein widely …

Marfan syndrome (MFS), a relatively common autosomal dominant hereditary disorder of
connective tissue with prominent manifestations in the skeletal, ocular, and cardiovascular …

Abstract Purpose of Review Marfan syndrome (MFS) is an autosomal dominant heritable
disorder of fibrillin-1 (FBN1) with predominantly ocular, cardiovascular, and musculoskeletal …

Background Marfan syndrome (MFS) is a disorder of autosomal dominant inheritance, in
which aortic root dilation is the main cause of morbidity and mortality. Fibrillin-1 (FBN-1) …

Background Cardiovascular complications account for a significant proportion of the
shortened lifespan of Marfan syndrome (MFS) patients, with aortic dissection being the most …

Marfan syndrome (MFS) is a genetic disorder that affects multiple organs. Mortality imposed
by aortic aneurysm and dissections represent the most serious clinical manifestation of MFS …

Marfan syndrome (MFS) is an autosomal dominant disorder of the connective tissue
characterized by early development of thoracic aortic aneurysms/dissections together with …