[HTML][HTML] Exploring the Central Mechanisms of Botulinum Toxin in Parkinson's Disease: A Systematic Review from Animal Models to Human Evidence

C Cutrona, F Marchet, M Costanzo, MI De Bartolo… - Toxins, 2023 - mdpi.com
Botulinum toxin (BoNT) is an effective and safe therapy for the symptomatic treatment of
several neurological disturbances. An important line of research has provided numerous …

Botulinum toxin therapy for nonmotor aspects of Parkinson's disease

J Sławek, M Madaliński - International Review of Neurobiology, 2017 - Elsevier
The medical treatment of Parkinson's disease (PD) is symptomatic both in terms of motor
and nonmotor aspects. The nonmotor symptoms therapy should be taken into account as …

[HTML][HTML] Botulinum Toxin for the Management of Parkinson's Disease: A Systematic Review

E Slouha, F Ibrahim, S Esposito, O Mursuli… - Cureus, 2024 - ncbi.nlm.nih.gov
Parkinson's disease (PD) is a terminal, debilitating neurodegenerative disorder typically
affecting individuals over 60. It is associated with various conditions that drastically affect the …

Efficacy and safety of botulinum toxin for treating motor dysfunction in patients with Parkinson's disease: a systematic review and meta-analysis

Y Yang, T Zhang, L Liu, L Shan, X Hu, L Yang, F Gao… - BMJ open, 2023 - bmjopen.bmj.com
Objective To evaluate the efficacy and safety of botulinum toxin (BTX) for motor dysfunction
in Parkinson's disease (PD). Design Systematic review and meta-analysis. Data sources …

Botulinum toxin therapy for parkinson's disease

AW Shukla, IA Malaty - Seminars in Neurology, 2017 - thieme-connect.com
Botulinum toxin (BoNT) therapy is frequently employed in the treatment of Parkinson's
disease (PD) symptoms. It can effectively ameliorate the symptoms of cervical dystonia …

How does botulinum toxin really work?

D Belvisi, G Leodori, M Costanzo, A Conte… - International Review of …, 2023 - Elsevier
Over the past 30 years, Botulinum toxin (BoNT) has emerged as an effective and safe
therapeutic tool for a number of neurological conditions, including dystonia. To date, the …

Use of botulinum toxin in the management of dystonia in Parkinson's disease

C Anandan, J Jankovic - Frontiers in Neuroscience, 2024 - frontiersin.org
Botulinum toxin is one of the most potent neurotoxins, but when injected into an overactive
muscle, it can transiently alleviate an involuntary movement, such as dystonia. The primary …

Botulinum toxin in the management of parkinsonian disorders

T Grippe, R Chen - Toxicon, 2023 - Elsevier
Many studies have shown that botulinum toxin (BoNT) can be an option to treat motor and
non-motor symptoms in Parkinson's disease (PD) and parkinsonian syndromes. The …

Comparison of Botulinum neurotoxin efficiency in dystonia associated with Parkinson's disease and atypical parkinsonism: a retrospective study with a self-reported …

A Lapostolle, M Houot, M Mongin, B Degos - Journal of Neurology, 2022 - Springer
Botulinum neurotoxin (BoNT) is a useful therapeutic option to treat dystonic manifestations.
Data on its efficiency on dystonia associated with Parkinson's disease (PD) or atypical …

[HTML][HTML] Experimental intrastriatal applications of botulinum neurotoxin-A: A review

A Hawlitschka, A Wree - International Journal of Molecular Sciences, 2018 - mdpi.com
Parkinson's disease (PD) is one of the most frequent neurodegenerative disorders. Its main
pathophysiological characteristic is the loss of dopaminergic neurons in the substantia nigra …