Extraction, isolation and in vitro evaluation of affinisine from Tabernaemontana catharinensis in human melanoma cells
PF Rosales, A Gower, MLR Benitez, BS Pacheco… - Bioorganic …, 2019 - Elsevier
Plant compounds have been identified as new drug prototypes. In this line, this work aimed
to isolate the indole alkaloid affinisine from Tabernaemontana catharinensis and test its …
to isolate the indole alkaloid affinisine from Tabernaemontana catharinensis and test its …
The Apoptotic Effect of 1'S-1'-Acetoxychavicol Acetate from Alpinia Conchigera on Human Cancer Cells
1'-(S)-1'-Acetoxychavicol acetate (ACA) isolated from the Malaysian ethno-medicinal plant
Alpinia conchigera Griff. was investigated for its potential as an anticancer drug. In this …
Alpinia conchigera Griff. was investigated for its potential as an anticancer drug. In this …
Synthesis of structurally diverse derivatives of aconitine-type diterpenoid alkaloids and their anti-proliferative effects on canine breast cancer cells
L Zhang, Y Xie, X Liang, L Yin, C He, Z Yin, G Yue… - Bioorganic …, 2023 - Elsevier
As one of the most common malignancies in female dogs, no drugs have been developed
specifically for the treatment of canine mammary carcinoma. In our previous study, a series …
specifically for the treatment of canine mammary carcinoma. In our previous study, a series …
Novel anticancer alkene lactone from Persea americana
Abstract Context: Persea americana Mill (Lauraceae) root bark is used in ethnomedicine for
a variety of diseases including cancer. Objective: To isolate and characterize the chemical …
a variety of diseases including cancer. Objective: To isolate and characterize the chemical …
Anti-proliferative activities of terpenoids isolated from Alisma orientalis and their structure-activity relationships
W Xu, T Li, JF Qiu, SS Wu, MQ Huang… - Anti-Cancer Agents …, 2015 - ingentaconnect.com
This study aimed to isolate terpenoids from Alisma orientalis (Sam.) Juzep. and elucidate
their antiproliferative activities, as well as structure-activity relationships. Fourteen …
their antiproliferative activities, as well as structure-activity relationships. Fourteen …
RETRACTED: Ailanthone Induces Cell Cycle Arrest and Apoptosis in Melanoma B16 and A375 Cells
W Liu, X Liu, Z Pan, D Wang, M Li, X Chen, L Zhou… - Biomolecules, 2019 - mdpi.com
Malignant melanoma is the most lethal type of skin cancer. Previous studies have shown
that ailanthone has potent antitumor activity in a variety of cell lines. However, the anti-tumor …
that ailanthone has potent antitumor activity in a variety of cell lines. However, the anti-tumor …
Antitumour activity of 2-dihydroailanthone from the bark of Ailanthus altissima against U251
R Wang, Q Xu, L Liu, X Liang, L Cheng… - Pharmaceutical …, 2016 - Taylor & Francis
Abstract Context The bark of Ailanthus altissima (Mill.) Swingle (Simaroubaceae) is
traditionally used to treat ascariasis, diarrhoea, spermatorrhoea, bleeding and …
traditionally used to treat ascariasis, diarrhoea, spermatorrhoea, bleeding and …
Structural Characterization and Anticancer Activity of a New Anthraquinone from Senna velutina (Fabaceae)
DTH Castro, DF Leite, D da Silva Baldivia… - Pharmaceuticals, 2023 - mdpi.com
In this study, a novel compound was isolated, identified, and its chemical structure was
determined from the extract of the roots of Senna velutina. In addition, we sought to evaluate …
determined from the extract of the roots of Senna velutina. In addition, we sought to evaluate …
Bio-guided search of active indole alkaloids from Tabernaemontana catharinensis: Antitumour activity, toxicity in silico and molecular modelling studies
PF Rosales, FF Marinho, A Gower, M Chiarello… - Bioorganic …, 2019 - Elsevier
Active plant metabolites have been used as prototype drugs. In this context,
Tabernaemontana catharinensis (Apocynaceae) has been highlighted because of the …
Tabernaemontana catharinensis (Apocynaceae) has been highlighted because of the …
Antitumor effects of baicalin on ovarian cancer cells through induction of cell apoptosis and inhibition of cell migration in vitro
C Gao, Y Zhou, H Li, X Cong… - Molecular …, 2017 - spandidos-publications.com
Baicalin, an active flavone isolated from Scutellaria baicalensis Georgi, has been
demonstrated to induce various beneficial biochemical effects such as anti‑inflammatory …
demonstrated to induce various beneficial biochemical effects such as anti‑inflammatory …