Objective To compare the therapeutic effectiveness of oral corticosteroids with that of
adrenocorticotrophic hormone for infantile spasms. Methods PubMed, Embase, Scopus, and …

Objective The limitations of adrenocorticotrophic hormone (ACTH) treatment for infantile
spasms (ISs), such as high costs, limited availability, and adverse effects (AEs), make it …

Adrenocorticotropic hormone (ACTH) and corticosteroids are the usual first-line treatment
options for infantile spasms. Despite significant differences, these agents are often lumped …

Aim To compare the efficacy and safety of prednisolone/prednisone and adrenocorticotropic
hormone (ACTH) in the treatment of infantile spasms using a meta‐analysis of randomized …

Background There is ongoing debate regarding the comparative effectiveness of
adrenocorticotropic hormone and prednisolone in the treatment of infantile spasms. With a …

Objective To compare the effectiveness and cost‐effectiveness of adrenocorticotropic
hormone (ACTH) and oral steroids as first‐line treatment for infantile spasm resolution, we …

Purpose This study investigated the short‐term response to a standardized hormonal
therapy protocol for treatment of infantile spasms. Methods Twenty‐seven children with …

Objectives This study aimed to test the hypothesis that high-dose prednisolone (4
mg/kg/day) may be more efficacious than usual-dose (2 mg/kg/day) prednisolone for spasm …

Aim We performed a systematic review and network meta‐analysis (NMA) to obtain
comparative effectiveness estimates and rankings of non‐surgical interventions used to treat …

Background Hormonal therapy is the treatment of choice in most patients with infantile
spasms, but the optimal way to provide this therapy is unclear. Intramuscular …