[HTML][HTML] Lipid droplets fuel SARS-CoV-2 replication and production of inflammatory mediators
SSG Dias, VC Soares, AC Ferreira… - PLoS …, 2020 - journals.plos.org
Viruses are obligate intracellular parasites that make use of the host metabolic machineries
to meet their biosynthetic needs. Thus, identifying the host pathways essential for the virus …
to meet their biosynthetic needs. Thus, identifying the host pathways essential for the virus …
[HTML][HTML] SARS-CoV-2 exploits host DGAT and ADRP for efficient replication
Abstract Coronavirus Disease 2019 (COVID-19) is predominantly a respiratory tract infection
that significantly rewires the host metabolism. Here, we monitored a cohort of COVID-19 …
that significantly rewires the host metabolism. Here, we monitored a cohort of COVID-19 …
Dissecting lipid metabolism alterations in SARS-CoV-2
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of the COVID-
19 pandemic that has infected over a hundred million people globally. There have been …
19 pandemic that has infected over a hundred million people globally. There have been …
[HTML][HTML] The roles of lipids in SARS-CoV-2 viral replication and the host immune response
The significant morbidity and mortality associated with severe acute respiratory syndrome
coronavirus 2 infection has underscored the need for novel antiviral strategies. Lipids play …
coronavirus 2 infection has underscored the need for novel antiviral strategies. Lipids play …
[HTML][HTML] A global lipid map reveals host dependency factors conserved across SARS-CoV-2 variants
A comprehensive understanding of host dependency factors for SARS-CoV-2 remains
elusive. Here, we map alterations in host lipids following SARS-CoV-2 infection using …
elusive. Here, we map alterations in host lipids following SARS-CoV-2 infection using …
[HTML][HTML] COVID‐19—Associated dyslipidemia: Implications for mechanism of impaired resolution and novel therapeutic approaches
AV Sorokin, SK Karathanasis, ZH Yang… - The FASEB …, 2020 - ncbi.nlm.nih.gov
The current coronavirus disease 2019 (COVID‐19) pandemic presents a global challenge
for managing acutely ill patients and complications from viral infection. Systemic …
for managing acutely ill patients and complications from viral infection. Systemic …
[HTML][HTML] Cholesterol-rich lipid rafts as platforms for SARS-CoV-2 entry
SN Palacios-Rapalo, LA De Jesus-Gonzalez… - Frontiers in …, 2021 - frontiersin.org
Since its appearance, the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2),
the causal agent of Coronavirus Disease 2019 (COVID-19), represents a global problem for …
the causal agent of Coronavirus Disease 2019 (COVID-19), represents a global problem for …
[HTML][HTML] The fatty acid lipid metabolism nexus in COVID-19
JE Tanner, C Alfieri - Viruses, 2021 - mdpi.com
Enteric symptomology seen in early-stage severe acute respiratory syndrome (SARS)-2003
and COVID-19 is evidence of virus replication occurring in the intestine, liver and pancreas …
and COVID-19 is evidence of virus replication occurring in the intestine, liver and pancreas …
Neurological aspects of SARS-CoV-2 infection: Lipoproteins and exosomes as Trojan horses
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) primarily targets lipid-
producing cells for viral tropism. In this review, we connect systemic lipid couriers …
producing cells for viral tropism. In this review, we connect systemic lipid couriers …
[HTML][HTML] The role of lipid metabolism in COVID-19 virus infection and as a drug target
M Abu-Farha, TA Thanaraj, MG Qaddoumi… - International journal of …, 2020 - mdpi.com
The current Coronavirus disease 2019 or COVID-19 pandemic has infected over two million
people and resulted in the death of over one hundred thousand people at the time of writing …
people and resulted in the death of over one hundred thousand people at the time of writing …