Beyond Spirometry: Linking Wasted Ventilation to Exertional Dyspnea in the Initial Stages of COPD
Exertional dyspnea, a key complaint of patients with chronic obstructive pulmonary disease
(COPD), ultimately reflects an increased inspiratory neural drive to breathe. In non …
(COPD), ultimately reflects an increased inspiratory neural drive to breathe. In non …
Ventilatory inefficiency and exertional dyspnea in early chronic obstructive pulmonary disease
Exertional dyspnea is present across the spectrum of chronic obstructive pulmonary disease
(COPD) severity. However, without realizing it themselves, patients may decrease daily …
(COPD) severity. However, without realizing it themselves, patients may decrease daily …
[HTML][HTML] Exertional ventilation/carbon dioxide output relationship in COPD: from physiological mechanisms to clinical applications
There is well established evidence that the minute ventilation (V′ E)/carbon dioxide output
(V′ CO 2) relationship is relevant to a number of patient-related outcomes in COPD. In most …
(V′ CO 2) relationship is relevant to a number of patient-related outcomes in COPD. In most …
Exertional dyspnoea in patients with mild‐to‐severe chronic obstructive pulmonary disease: neuromechanical mechanisms
MD James, DB Phillips, SG Vincent… - The Journal of …, 2022 - Wiley Online Library
In patients with chronic obstructive pulmonary disease (COPD), exertional dyspnoea
generally arises when there is imbalance between ventilatory demand and capacity, but the …
generally arises when there is imbalance between ventilatory demand and capacity, but the …
Mechanisms of Exertional Dyspnea in Patients with Mild COPD and a Low Resting DLCO
Patients with mild chronic obstructive pulmonary disease (COPD) and lower resting diffusing
capacity for carbon monoxide (DLCO) often report troublesome dyspnea during exercise …
capacity for carbon monoxide (DLCO) often report troublesome dyspnea during exercise …
Inspiratory constraints and ventilatory inefficiency are superior to breathing reserve in the assessment of exertional dyspnea in COPD
Combining measurements of impaired lung mechanics (inspiratory constraints) with an
index of increased respiratory stimuli to metabolic demand (poor ventilatory efficiency) might …
index of increased respiratory stimuli to metabolic demand (poor ventilatory efficiency) might …
Resting V′ E/V′ CO2 adds to inspiratory capacity to predict the burden of exertional dyspnoea in COPD
Exertional dyspnoea is a cardinal symptom of patients with COPD [1]. Incremental
cardiopulmonary exercise testing (CPET), in particular, might provide useful mechanistic …
cardiopulmonary exercise testing (CPET), in particular, might provide useful mechanistic …
Exertional dyspnoea in patients with airway obstruction, with and without CO2 retention
SGM Cloosterman, ID Hofland, CP Van Schayck… - Thorax, 1998 - thorax.bmj.com
BACKGROUND Dyspnoea is a common and disabling symptom in patients with
cardiopulmonary disease. Unfortunately the mechanisms that produce dyspnoea are still …
cardiopulmonary disease. Unfortunately the mechanisms that produce dyspnoea are still …
Too rapid increase and too much breathlessness are distinct indices of exertional dyspnea in COPD
C Delclaux, B Chevalier-Bidaud, M Essalhi… - Respiratory physiology …, 2011 - Elsevier
To assess whether different indices of dyspnea can be obtained from cardiopulmonary
exercise test and whether these indices correlate with distinct physiological parameters in …
exercise test and whether these indices correlate with distinct physiological parameters in …
Chronic effort dyspnea explained by lung function tests and by HRCT and CRX radiographic patterns in COPD: a post-hoc analysis in 51 patients
C Giuntini, G Camiciottoli, NM Maluccio… - COPD: Journal of …, 2007 - Taylor & Francis
This paper is a post-hoc analysis of a previous study performed to investigate the
relationship between computerized tomography (CT) and lung function in 51 outpatients …
relationship between computerized tomography (CT) and lung function in 51 outpatients …