On the function and relevance of alternative 3′‐UTRs in gene expression regulation
I Pereira‐Castro, A Moreira - Wiley Interdisciplinary Reviews …, 2021 - Wiley Online Library
Messanger RNA (mRNA) isoforms with alternative 3′‐untranslated regions (3′‐UTRs) are
produced by alternative polyadenylation (APA), which occurs during transcription in most …
produced by alternative polyadenylation (APA), which occurs during transcription in most …
Context-specific regulation and function of mRNA alternative polyadenylation
S Mitschka, C Mayr - Nature Reviews Molecular Cell Biology, 2022 - nature.com
Alternative cleavage and polyadenylation (APA) is a widespread mechanism to generate
mRNA isoforms with alternative 3′ untranslated regions (UTRs). The expression of …
mRNA isoforms with alternative 3′ untranslated regions (UTRs). The expression of …
Alternative polyadenylation: An enigma of transcript length variation in health and disease
NK Mohanan, F Shaji, GR Koshre… - Wiley Interdisciplinary …, 2022 - Wiley Online Library
Alternative polyadenylation (APA) is a molecular mechanism during a pre‐mRNA
processing that involves usage of more than one polyadenylation site (PA‐site) generating …
processing that involves usage of more than one polyadenylation site (PA‐site) generating …
The role of alternative polyadenylation in the regulation of subcellular RNA localization
Alternative polyadenylation (APA) is a widespread and conserved regulatory mechanism
that generates diverse 3′ ends on mRNA. APA patterns are often tissue specific and play …
that generates diverse 3′ ends on mRNA. APA patterns are often tissue specific and play …
Regulation and function of alternative polyadenylation in development and differentiation
L Gallicchio, GH Olivares, CW Berry, MT Fuller - RNA biology, 2023 - Taylor & Francis
Alternative processing of nascent mRNAs is widespread in eukaryotic organisms and greatly
impacts the output of gene expression. Specifically, alternative cleavage and …
impacts the output of gene expression. Specifically, alternative cleavage and …
Global insights into alternative polyadenylation regulation
Alternative pre-mRNA processing greatly increases the coding capacity of the human
genome and regulatory factors involved in RNA processing play critical roles in tissue …
genome and regulatory factors involved in RNA processing play critical roles in tissue …
[HTML][HTML] Alternative polyadenylation of mRNAs: 3'-untranslated region matters in gene expression
HS Yeh, J Yong - Molecules and cells, 2016 - Elsevier
Almost all of eukaryotic mRNAs are subjected to polyadenylation during mRNA processing.
Recent discoveries showed that many of these mRNAs contain more than one …
Recent discoveries showed that many of these mRNAs contain more than one …
Alternative cleavage and polyadenylation: extent, regulation and function
The 3′ end of most protein-coding genes and long non-coding RNAs is cleaved and
polyadenylated. Recent discoveries have revealed that a large proportion of these genes …
polyadenylated. Recent discoveries have revealed that a large proportion of these genes …
Mechanisms and consequences of alternative polyadenylation
DC Di Giammartino, K Nishida, JL Manley - Molecular cell, 2011 - cell.com
Alternative polyadenylation (APA) is emerging as a widespread mechanism used to control
gene expression. Like alternative splicing, usage of alternative poly (A) sites allows a single …
gene expression. Like alternative splicing, usage of alternative poly (A) sites allows a single …
[HTML][HTML] Sequential Polyadenylation to Enable Alternative mRNA 3'End Formation
In eukaryotic cells, a key RNA processing step to generate mature mRNA is the coupled
reaction for cleavage and polyadenylation (CPA) at the 3′ end of individual transcripts …
reaction for cleavage and polyadenylation (CPA) at the 3′ end of individual transcripts …