[HTML][HTML] Simultaneous administration of dexamethasone and vitamin E reversed experimental varicocele-induced impact in testicular tissue in rats; correlation with …

H Khosravanian, M Razi, F Farokhi… - International braz j …, 2015 - SciELO Brasil
Purpose: This study aimed to investigate the protective effects of isolated and co-
administration of vitamin E (VitE) and dexamethasone (DEX) on varicocele (VCL)-induced …

Testosterone and vitamin E administration up-regulated varicocele-reduced Hsp70-2 protein expression and ameliorated biochemical alterations

N Khosravanian, M Razi, F Farokhi… - Journal of assisted …, 2014 - Springer
Purpose This study was designed to evaluate the protective effects of vitamin E (VitE) and
testosterone on varicocele (VCL)-induced damage in testis and sperm parameters and their …

Evaluation of oxidative stress in testis and sperm of rat following induced varicocele

NE Majd, N Sadeghi, M Tavalaee, MR Tabandeh… - Urology …, 2019 - ojs3.sbmu.ac.ir
Purpose: Oxidative stress (OS) plays a central role in the pathophysiology of varicocele
(VC), however, comprehensive studies concomitantly assessing semen parameter along …

Silymarin and celecoxib ameliorate experimental varicocele-induced pathogenesis: evidences for oxidative stress and inflammation inhibition

S Mazhari, M Razi, R Sadrkhanlou - International urology and nephrology, 2018 - Springer
Background The present study was done to investigate the ameliorative effect of silymarin
(SMN) and celecoxib (CEL) on varicocele (VCL)-induced detrimental impact in testicular …

[HTML][HTML] Beneficial effects of combination therapy with testosterone and hydrogen sulfide by reducing oxidative stress and apoptosis: Rat experimental varicocele …

A Shafie, F Kianian, G Ashabi… - International Journal …, 2022 - ncbi.nlm.nih.gov
Background Despite the effectiveness of testosterone therapy in conditions associated with
testosterone deficiency, including varicocele, several dose-dependent side effects limit the …

Testicular hypofunction caused by activating p53 expression induced by reactive oxygen species in varicocele rats

M Liang, J Wen, Q Dong, LG Zhao, BK Shi - Andrologia, 2015 - Wiley Online Library
We investigated the mechanism of the testicular hypofunction induced by hypoxia in
varicocele rats. Varicocele was induced by partial ligation of the left renal vein. Seven weeks …

Silymarin protects from varicocele-induced damages in testis and improves sperm quality: evidence for E2f1 involvement

SM Moshtaghion, H Malekinejad, M Razi… - Systems biology in …, 2013 - Taylor & Francis
This study was designed to evaluate the protective effect of silymarin (SMN) on varicocele-
induced damage in testis and its effects on sperm parameters and on antioxidant status …

Lycopene improves testicular damage and sperm quality in experimentally induced varicocele: Relationship with apoptosis, hypoxia, and hyperthermia

A Babaei, R Asadpour, K Mansouri… - Food science & …, 2022 - Wiley Online Library
Varicocele is considered the main reason for male infertility. Antioxidants are common drugs
used to reduce the complications of varicocele in these patients. So, we investigated the …

Testosterone amplifies HSP70-2a, HSP90 and PCNA expression in experimental varicocele condition: Implication for DNA fragmentation

S Salmani, M Razi, F Sarrafzadeh-Rezaei… - Reproductive …, 2020 - Elsevier
The DNA fragmentation and failure in post-meiotic maturation of the spermatozoa because
of testosterone withdrawal can affect the fertilization potential in varicocele (VCL) patients …

Effect of varicocelectomy treatment on spermatogenesis and apoptosis via the induction of heat shock protein 70 in varicocele‑induced rats

JZ Ning, T Rao, F Cheng, WM Yu… - Molecular …, 2017 - spandidos-publications.com
In the current study, the hypothesis that testicular varicocelectomy improves
spermatogenesis and attenuates apoptosis via the induction of heat shock protein 70 …