Blood pressure (BP) is a complex trait regulated by an intricate network of physiological
pathways involving extracellular fluid volume homeostasis, cardiac contractility and vascular …

Hypertension (HTN) is quantitatively the major cardiovascular risk factor and responsible
for∼ 50% of cardiovascular morbidity and mortality. Blood pressure (BP) is also a classical …

High blood pressure (BP) remains the major heritable and modifiable risk factor for
cardiovascular disease. Persistent high BP, or hypertension, is a complex trait with both …

Hypertension, or elevated blood pressure, constitutes a major public health burden that
affects more than 1 billion people worldwide and contributes to~ 9 million deaths annually …

Until recently, significant advances in our understanding of the mechanisms of blood
pressure regulation arose from studies of monogenic forms of hypertension and …

Hypertension has become a major global health burden due to its high prevalence and
associated increase in risk of cardiovascular disease and premature death. It is well …

A complex network of interacting pathways involving renal, neural, endocrine, vascular and
other mechanisms controls the main determinants of blood pressure–cardiac output and …

The elucidation of genes implicated in Mendelian forms of hypertension demonstrates rare
variants with substantial effects are responsible, and often these genes lie within pathways …

The heritability of hypertension (HTN) is widely recognized and as a result, extensive studies
ranging from genetic linkage analyses to genome-wide association studies are actively …

Abstract Blood pressure (BP), hypertension (HT) and cardiovascular disease (CVD) are
common complex phenotypes, which are affected by multiple genetic and environmental …