Condensed DNA: condensing the concepts
DNA is stored in vivo in a highly compact, so-called condensed phase, where gene
regulatory processes are governed by the intricate interplay between different states of DNA …
regulatory processes are governed by the intricate interplay between different states of DNA …
[HTML][HTML] DNA length tunes the fluidity of DNA-based condensates
F Muzzopappa, M Hertzog, F Erdel - Biophysical journal, 2021 - cell.com
Living organisms typically store their genomic DNA in a condensed form. Mechanistically,
DNA condensation can be driven by macromolecular crowding, multivalent cations, or …
DNA condensation can be driven by macromolecular crowding, multivalent cations, or …
DNA condensation
VA Bloomfield - Current opinion in structural biology, 1996 - Elsevier
Recent progress in our understanding of DNA condensation includes the observation of the
collapse of single DNA molecules, greater insights into the intermolecular forces driving …
collapse of single DNA molecules, greater insights into the intermolecular forces driving …
The structure and intermolecular forces of DNA condensates
J Yoo, A Aksimentiev - Nucleic acids research, 2016 - academic.oup.com
Spontaneous assembly of DNA molecules into compact structures is ubiquitous in biological
systems. Experiment has shown that polycations can turn electrostatic self-repulsion of DNA …
systems. Experiment has shown that polycations can turn electrostatic self-repulsion of DNA …
Electrostatics of DNA compaction in viruses, bacteria and eukaryotes: functional insights and evolutionary perspective
The molecular support of genetic information, DNA, has to be packaged and organized
inside the tiny volume of nuclei, cells, or virus capsids, in an ordered and dynamical way …
inside the tiny volume of nuclei, cells, or virus capsids, in an ordered and dynamical way …
DNA compaction: fundamentals and applications
A Estévez-Torres, D Baigl - Soft Matter, 2011 - pubs.rsc.org
Compaction is the process in which a large DNA molecule undergoes a transition between
an elongated conformation and a very compact form. In nature, DNA compaction occurs to …
an elongated conformation and a very compact form. In nature, DNA compaction occurs to …
DNA condensation in bacteria: Interplay between macromolecular crowding and nucleoid proteins
R De Vries - Biochimie, 2010 - Elsevier
The volume of a typical Eschericia coli nucleoid is roughly 104 times smaller than the
volume of a freely coiling linear DNA molecule with the same length as the E. coli genome …
volume of a freely coiling linear DNA molecule with the same length as the E. coli genome …
DNA condensation by multivalent cations
VA Bloomfield - Biopolymers: Original Research on …, 1997 - Wiley Online Library
In the presence of multivalent cations, high molecular weight DNA undergoes a dramatic
condensation to a compact, usually highly ordered toroidal structure. This review begins with …
condensation to a compact, usually highly ordered toroidal structure. This review begins with …
[HTML][HTML] Real-time detection of single-molecule DNA compaction by condensin I
TR Strick, T Kawaguchi, T Hirano - Current biology, 2004 - cell.com
Background: Condensin is thought to contribute to large-scale DNA compaction during
mitotic chromosome assembly. It remains unknown, however, how the complex reconfigures …
mitotic chromosome assembly. It remains unknown, however, how the complex reconfigures …
Bubbles and denaturation in DNA
TS Van Erp, S Cuesta-Lopez, M Peyrard - The European Physical Journal …, 2006 - Springer
The local opening of DNA is an intriguing phenomenon from a statistical-physics point of
view, but is also essential for its biological function. For instance, the transcription and …
view, but is also essential for its biological function. For instance, the transcription and …