Condensed DNA: condensing the concepts

VB Teif, K Bohinc - Progress in biophysics and molecular biology, 2011 - Elsevier
DNA is stored in vivo in a highly compact, so-called condensed phase, where gene
regulatory processes are governed by the intricate interplay between different states of DNA …

[HTML][HTML] DNA length tunes the fluidity of DNA-based condensates

F Muzzopappa, M Hertzog, F Erdel - Biophysical journal, 2021 - cell.com
Living organisms typically store their genomic DNA in a condensed form. Mechanistically,
DNA condensation can be driven by macromolecular crowding, multivalent cations, or …

DNA condensation

VA Bloomfield - Current opinion in structural biology, 1996 - Elsevier
Recent progress in our understanding of DNA condensation includes the observation of the
collapse of single DNA molecules, greater insights into the intermolecular forces driving …

The structure and intermolecular forces of DNA condensates

J Yoo, A Aksimentiev - Nucleic acids research, 2016 - academic.oup.com
Spontaneous assembly of DNA molecules into compact structures is ubiquitous in biological
systems. Experiment has shown that polycations can turn electrostatic self-repulsion of DNA …

Electrostatics of DNA compaction in viruses, bacteria and eukaryotes: functional insights and evolutionary perspective

P Carrivain, A Cournac, C Lavelle, A Lesne… - Soft Matter, 2012 - pubs.rsc.org
The molecular support of genetic information, DNA, has to be packaged and organized
inside the tiny volume of nuclei, cells, or virus capsids, in an ordered and dynamical way …

DNA compaction: fundamentals and applications

A Estévez-Torres, D Baigl - Soft Matter, 2011 - pubs.rsc.org
Compaction is the process in which a large DNA molecule undergoes a transition between
an elongated conformation and a very compact form. In nature, DNA compaction occurs to …

DNA condensation in bacteria: Interplay between macromolecular crowding and nucleoid proteins

R De Vries - Biochimie, 2010 - Elsevier
The volume of a typical Eschericia coli nucleoid is roughly 104 times smaller than the
volume of a freely coiling linear DNA molecule with the same length as the E. coli genome …

DNA condensation by multivalent cations

VA Bloomfield - Biopolymers: Original Research on …, 1997 - Wiley Online Library
In the presence of multivalent cations, high molecular weight DNA undergoes a dramatic
condensation to a compact, usually highly ordered toroidal structure. This review begins with …

[HTML][HTML] Real-time detection of single-molecule DNA compaction by condensin I

TR Strick, T Kawaguchi, T Hirano - Current biology, 2004 - cell.com
Background: Condensin is thought to contribute to large-scale DNA compaction during
mitotic chromosome assembly. It remains unknown, however, how the complex reconfigures …

Bubbles and denaturation in DNA

TS Van Erp, S Cuesta-Lopez, M Peyrard - The European Physical Journal …, 2006 - Springer
The local opening of DNA is an intriguing phenomenon from a statistical-physics point of
view, but is also essential for its biological function. For instance, the transcription and …