Our understanding of the process of autophagy and its role in health and diseases has
grown remarkably in the last two decades. Early work established autophagy as a general …

Macroautophagy (autophagy) is a conserved lysosomal degradation process essential for
cellular homeostasis and adaption to stress. Accumulating evidence indicates that …

Autophagy is a critical quality control pathway that is conserved across diverse systems
ranging from simple unicellular organisms like yeast to more complex systems, for instance …

Aging is associated with many deleterious changes at the cellular level, including the
accumulation of potentially toxic components that can have devastating effects on health. A …

Autophagy, an essential cellular process that mediates degradation of proteins and
organelles in lysosomes, has been tightly linked to cellular quality control for its role as part …

Autophagy is a fundamental cellular process that eliminates molecules and subcellular
elements, including nucleic acids, proteins, lipids and organelles, via lysosome-mediated …

Autophagy is a process of cellular self-degradation in which portions of the cytoplasm are
sequestered within cytosolic double-membrane vesicles and delivered to the …

Autophagy (ATG) is the process of bulk degradation and recycling of long-lived proteins,
macromolecular aggregates, and damaged intracellular organelles. Cellular homeostasis …

Autophagy and cellular senescence are stress responses essential for homeostasis. While
recent studies indicate a genetic relationship between autophagy and senescence, whether …

Autophagy is a major protein turnover pathway by which cellular components are delivered
into the lysosomes for degradation and recycling. This intracellular process is able to …