Systemic lupus erythematosus (SLE) is a chronic, devastating autoimmune disorder
associated with severe organ damage. Recently, the role of Signal Transducer and Activator …

Background and purpose The balance between T helper 17 (Th17) cells and regulatory T
(Treg) cells, plays a critical role in rheumatoid arthritis (RA). The differentiation of Th17 cells …

Osteoarthritis (OA) is a common degenerative disease characterized by progressive erosion
of articular cartilage, subchondral bone sclerosis and synovitis. Cryptotanshinone (CTS), an …

The discovery of new therapeutic drugs with the efficacious and safe ability to prevent
epidermal hyperplasia is extremely urgent for psoriasis. Cryptotanshinone (CTS), an active …

The discovery of new therapeutic drugs with the ability of preventing inflammation and joint
destruction with less adverse effects is extremely urgent for rheumatoid arthritis (RA) …

Systemic lupus erythematosus (SLE) is a devastating autoimmune disorder associated with
severe organ damage. The abnormality of T cell apoptosis is considered as an important …

Background Cryptotanshinone (CT) was originally isolated from the dried roots of Salvia
militorrhiza, an herb that is used extensively in Asian medicine and the extracts of this herb …

Background Autoantibody production against endogenous cellular components is
pathogenic feature of systemic lupus erythematosus (SLE). Follicular helper T (T FH) cells …

3, 4-dimethoxycinnamonyl-anthranilic acid (tranilast) is an orally available anti-allergic drug
with structural and functional homologies to immunosuppressive catabolites of the essential …

Ulcerative colitis (UC) is a chronically relapsing inflammatory disease in the intestinal tract.
Current unsatisfactory treatments prompt people to seek for alternative therapies and drug …