I. Introduction IT HAS been known for several years that steroid hormones function through
the action of specific receptor proteins. In target tissues, receptors are activated by hormonal …

I. Introduction Steroid hormones act on a wide variety of target cells to alter their structure
and function in remarkably diverse ways. However, much evidence has accumulated to …

The steroid receptor superfamily of ligand‐dependent transcription factors is characterized
by marked conservation of both structure and function between the various receptors …

The cumbersome nature of many pharmacological tests has seriously limited the full-scale
study of the hormonal activity profile of a large number of molecules. To overcome this …

Because of the intimidating complexity of homeostatic regulation, the modern researcher in
the life sciences is generally obliged to consider physiological phenomena in the most …

The steroid/thyroid hormone receptor superfamily of ligand-activated transcription factors
encompasses not only the receptors for steroids, thyroid hormone, retinoids and vitamin D …

Several years passed between the pioneer report demonstrating the existence of
glucocorticoid receptor and correlation between intracellular ATP levels and hormone …

This review has highlighted several topics in the study of steroid hormone action. The
unanswered questions regarding the mechanism of ligand-controlled LRF activity, the extent …

Publisher Summary Current biochemical evidence favors a common molecular mechanism
for all the steroid hormones. The steroid binds tightly and specifically to a cytoplasmic …

Receptors for steroid hormones differ markedly from membrane receptors in that they are
intracellular and act primarily by regula-tion of DNA transcription. Like membrane receptors …