Alzheimer disease (AD) is the most common cause of dementia, characterized by a
progressive decline in cognitive function due to the abnormal aggregation and deposition of …

Alzheimer's disease is the most common form of dementia. Its aetiology is characterized by
the misfolding and aggregation of amyloid-β (Aβ) peptides into β-sheet-rich Aβ …

Abnormal protein aggregation in the nervous tissue leads to several neurodegenerative
disorders like Alzheimer's disease (AD). In AD, accumulation of the amyloid beta (Aβ) …

A broad range of human diseases, including Alzheimer's and Parkinson's diseases, arise
from or have as key players intrinsically disordered proteins. The aggregation of these …

Lipid membranes play a fundamental role in the pathological development of protein
misfolding diseases. Several pieces of evidence suggest that the lipid membrane could act …

The interactions of amyloid peptides with cell membranes play an important role in
maintaining the integrity and functionality of cell membrane. A thorough molecular-level …

Fibrillar aggregates of misfolded amyloid proteins are involved in a variety of diseases such
as Alzheimer disease (AD), type 2 diabetes, Parkinson, Huntington and prion-related …

Accumulation of protein-based (Aβ) aggregates on cellular membranes with varying
structural properties is commonly recognized as the key step in Alzheimer's pathogenesis …

Several neurodegenerative disorders arise from the abnormal protein aggregation in the
nervous tissue leading tointracellular inclusions or extracellular aggregates in specific brain …

Amyloid-β (Aβ) peptides are thought to be involved in neurodegenerative diseases such as
Alzheimer's disease and Down's syndrome. They form a large number of polymorphic …