The endocannabinoid system as possible target for the treatment of obesity related disorders: beyond cannabinoid receptors

M de Ceglia - 2021 - iris.uniroma1.it
Worldwide, obesity is one of the most diffused pathologies. Several lines of recent evidence
link obesity with a higher risk of neurological pathologies such as anxiety and depression; …

[HTML][HTML] Obesity as a Condition determined by Food Addiction: should Brain Endocannabinoid System alterations be the cause and its Modulation the Solution?

M de Ceglia, J Decara, S Gaetani… - Pharmaceuticals, 2021 - mdpi.com
Obesity is a complex disorder, and the number of people affected is growing every day. In
recent years, research has confirmed the hypothesis that food addiction is a determining …

Anxiety associated with palatable food withdrawal is reversed by the selective FAAH inhibitor PF‐3845: A regional analysis of the contribution of endocannabinoid …

M De Ceglia… - … Journal of Eating …, 2023 - Wiley Online Library
Objective Consumption of energy‐dense palatable “comfort” food can alleviate stress and
negative emotions, while abrupt withdrawal from a palatable diet can worsen these …

The role of the endocannabinoid system in eating disorders: pharmacological implications

EM Marco, SY Romero-Zerbo, MP Viveros… - Behavioural …, 2012 - journals.lww.com
The endocannabinoid (eCB) system is a widespread intercellular signalling mechanism that
plays a critical role in body homoeostasis. It is located in key points involved in food intake …

Endocannabinoid system and eating behavior/Sistema endocannabinoide y conducta alimentaria

J Ramírez-Emiliano, IG Ortega-Barrón… - 2024 - journals.iztacala.unam.mx
The objective of this systematic review was to investigate previously published literature that
examined the effect of hypercaloric diet on the endocannabinoid system, eating behavior …

Peripheral endocannabinoids in eating disorders and obesity and its relationship with clinical and anthropometric variables

I Baenas-Soto, R Miranda-Olivos, L Vos… - European …, 2021 - cambridge.org
IntroductionAnandamide (AEA) and 2-Arachidonoylglycerol (2-AG) play a pivotal role in food
intake and reward aspects of feeding. Aberrant functioning in the endocannabinoid system …

Endogenous cannabinoid system as a modulator of food intake

D Cota, G Marsicano, B Lutz, V Vicennati… - International journal of …, 2003 - nature.com
The ability of Cannabis sativa (marijuana) to increase hunger has been noticed for
centuries, although intensive research on its molecular mode of action started only after the …

Changes in the peripheral endocannabinoid system as a risk factor for the development of eating disorders

A Capasso, W Milano, O Cauli - Endocrine, Metabolic & …, 2018 - ingentaconnect.com
Background and Objective: Eating Disorder (ED) is characterized by persistently and
severely disturbed eating behaviours. They arise from a combination of long-standing …

[HTML][HTML] Blood levels of the endocannabinoid anandamide are increased in anorexia nervosa and in binge-eating disorder, but not in bulimia nervosa

P Monteleone, I Matias, V Martiadis… - …, 2005 - nature.com
The endocannabinoid system, consisting of two cannabinoid receptors (CB 1 and CB 2) and
the endogenous ligands anandamide (arachidonoylethanolamide (AEA)) and 2 …

[HTML][HTML] The endocannabinoid system as pharmacological target derived from its CNS role in energy homeostasis and reward. Applications in eating disorders and …

MP Viveros, FJ Bermúdez-Silva, AB Lopez-Rodriguez… - Pharmaceuticals, 2011 - mdpi.com
The endocannabinoid system (ECS) has been implicated in many physiological functions,
including the regulation of appetite, food intake and energy balance, a crucial involvement in …