The effects of protein corona on in vivo fate of nanocarriers
With the emerging advances in utilizing nanocarriers for biomedical applications, a
molecular-level understanding of the in vivo fate of nanocarriers is necessary. After …
molecular-level understanding of the in vivo fate of nanocarriers is necessary. After …
Protein corona on brain targeted nanocarriers: challenges and prospects
K Jiang, Y Yu, W Qiu, K Tian, Z Guo, J Qian… - Advanced Drug Delivery …, 2023 - Elsevier
Safe and efficient medical therapy for brain diseases is still an unmet clinical need due to
various barriers represented by the blood-brain barrier. Well-designed brain targeted …
various barriers represented by the blood-brain barrier. Well-designed brain targeted …
The impact of protein corona on the biological behavior of targeting nanomedicines
For successful translation of targeting nanomedicines from bench to bedside, it is vital to
address their most common drawbacks namely rapid clearance and off-target accumulation …
address their most common drawbacks namely rapid clearance and off-target accumulation …
[HTML][HTML] The Yin and Yang of the protein corona on the delivery journey of nanoparticles
Nanoparticles-based drug delivery systems have attracted significant attention in biomedical
fields because they can deliver loaded cargoes to the target site in a controlled manner …
fields because they can deliver loaded cargoes to the target site in a controlled manner …
Controlling the stealth effect of nanocarriers through understanding the protein corona
S Schöttler, K Landfester… - Angewandte Chemie …, 2016 - Wiley Online Library
The past decade has seen a significant increase in interest in the use of polymeric
nanocarriers in medical applications. In particular, when used as drug vectors in targeted …
nanocarriers in medical applications. In particular, when used as drug vectors in targeted …
[HTML][HTML] Research progress and application opportunities of nanoparticle–protein corona complexes
W Huang, G Xiao, Y Zhang, W Min - Biomedicine & Pharmacotherapy, 2021 - Elsevier
Nanoparticles (NPs) can be used to design for nanomedicines with different chemical
surface properties owing to their size advantages and the capacity of specific delivery to …
surface properties owing to their size advantages and the capacity of specific delivery to …
Unveiling the pitfalls of the protein corona of polymeric drug nanocarriers
The protein corona is a natural protein layer spontaneously formed around nanomaterials
when exposed to biological media. This layer can alter the nanosystems' biological …
when exposed to biological media. This layer can alter the nanosystems' biological …
[HTML][HTML] Impact of protein corona on the biological identity of nanomedicine: understanding the fate of nanomaterials in the biological milieu
Nanoparticles (NPs) in contact with a biological medium are rapidly comprehended by a
number of protein molecules resulting in the formation of an NP–protein complex called …
number of protein molecules resulting in the formation of an NP–protein complex called …
Ligand size and conformation affect the behavior of nanoparticles coated with in vitro and in vivo protein corona
Protein corona is immediately established on the surface of nanoparticles upon their
introduction into biological milieu. Several studies have shown that the targeting efficiency of …
introduction into biological milieu. Several studies have shown that the targeting efficiency of …
The impact of protein corona on the behavior and targeting capability of nanoparticle-based delivery system
W Xiao, H Gao - International Journal of Pharmaceutics, 2018 - Elsevier
Once introduced into physiological environment, nanoparticles (NPs) are immediately
coated with proteins, resulting in formation of what is known as protein corona. The …
coated with proteins, resulting in formation of what is known as protein corona. The …
相关搜索
- protein corona fate of nanomaterials
- protein corona stealth effect
- protein corona drug nanocarriers
- protein corona biological behavior
- protein corona ligand size
- protein corona yin and yang
- protein corona challenges and prospects
- protein corona behavior of nanoparticles
- protein corona biological milieu
- protein corona biological identity