Leading Paediatric Infectious Diseases—Current Trends, Gaps, and Future Prospects in Oral Pharmacotherapeutic Interventions
PN Rampedi, MO Ogunrombi, OA Adeleke - Pharmaceutics, 2024 - mdpi.com
Paediatric infectious diseases contribute significantly to global health challenges.
Conventional therapeutic interventions are not always suitable for children, as they are …
Conventional therapeutic interventions are not always suitable for children, as they are …
Improving drug delivery in paediatric medicine
J Krause, J Breitkreutz - Pharmaceutical Medicine, 2008 - Springer
A major challenge in drug development is paediatric drug delivery; however, the problems
associated with drug administration in this population are manifold. Because of the highly …
associated with drug administration in this population are manifold. Because of the highly …
Opportunities for enteral drug delivery for neonates, infants, and toddlers: a critical exploration
Introduction The field of neonatal, infant and toddler pharmaceutical development is
constantly improving, however a lag still remains in comparison to older children and adults …
constantly improving, however a lag still remains in comparison to older children and adults …
Issues impacting therapeutic outcomes in pediatric patients: an overview
A Kalra, S Goindi - Current Pediatric Reviews, 2014 - ingentaconnect.com
The quest for achieving optimal therapeutic outcomes in pediatric patients has evaded the
healthcare professionals for long and often lack of child specific dosage forms and the …
healthcare professionals for long and often lack of child specific dosage forms and the …
Neonatal and pediatric oral drug delivery: Hopes and hurdles
The neonatal and pediatric populations have long been neglected concerning the
development of oral dosage forms. For close to two decades, caregivers have had to adjust …
development of oral dosage forms. For close to two decades, caregivers have had to adjust …
Drug Formulation for Pediatric Oral Antimicrobial Agents in Japan: Current Status, Prospects, and Challenges
J Saito, K Shoji, I Miyairi… - The Pediatric Infectious …, 2023 - journals.lww.com
The development of antibiotics that are acceptable and easy for children to take and use is
highly desirable. As advocated by the World Health Organization, solid oral formulations …
highly desirable. As advocated by the World Health Organization, solid oral formulations …
Pediatric drug development and dosage form design
M Preis, J Breitkreutz - AAPS PharmSciTech, 2017 - Springer
For many years, children have been described as Btherapeutic orphans^ to indicate that
medicinal research, regulation, and formulation development has mainly focused on …
medicinal research, regulation, and formulation development has mainly focused on …
Formulation approaches to pediatric oral drug delivery: benefits and limitations of current platforms
Introduction: Most conventional drug delivery systems are not acceptable for pediatric
patients as they differ in their developmental status and dosing requirements from other …
patients as they differ in their developmental status and dosing requirements from other …
Drug delivery and formulations
J Breitkreutz, J Boos - Pediatric Clinical Pharmacology, 2011 - Springer
Paediatric drug delivery is a major challenge in drug development. Because of the
heterogeneous nature of the patient group, ranging from newborns to adolescents, there is a …
heterogeneous nature of the patient group, ranging from newborns to adolescents, there is a …
Pediatric drug formulations: a review of challenges and progress
V Ivanovska, CMA Rademaker, L van Dijk… - …, 2014 - publications.aap.org
Children differ from adults in many aspects of pharmacotherapy, including capabilities for
drug administration, medicine-related toxicity, and taste preferences. It is essential that …
drug administration, medicine-related toxicity, and taste preferences. It is essential that …