Introduction Complement 3 glomerulopathy (C3G) is a rare kidney disease characterized by
dysregulation of the alternative pathway (AP) of the complement system. About 50% of …

Introduction Complement 3 glomerulopathy (C3G) is a rare inflammatory kidney disease
mediated by dysregulation of the alternative complement pathway. No targeted therapy …

Introduction Dysregulated complement activation is likely the primary driver of disease in C3
glomerulopathy (C3G) and contributes to other complement-mediated diseases, including …

C3 glomerulopathy (C3G) is a newly defined clinical entity comprising glomerular lesions
with predominant C3 staining. Under this definition are now included membranoproliferative …

The C3 glomerulopathies are a group of rare kidney diseases characterized by complement
dysregulation occurring in the fluid phase and in the glomerular microenvironment, which …

Abstract C3 glomerulopathy (C3G) is a recently identified disease entity caused by
dysregulation of the alternative complement pathway, and dense deposit disease (DDD) …

Abstract Introduction: C3 glomerulopathy (C3G) is an ultrarare, chronic and progressive
nephropathy mediated by dysregulation of the alternative pathway of complement (AP), with …

Abstract C3 glomerulopathy (C3G) is a clinicopathologic entity secondary to dysregulation of
the alternative complement pathway in plasma and the glomerular microenvironment. The …

ABSTRACT A refined understanding of the role of complement in the pathogenesis of
glomerular and other kidney diseases has, over the past two decades, been matched by the …

C3 glomerulopathy refers to a disease process in which abnormal control of complement
activation, degradation or deposition results in predominant C3 fragment deposition within …