Influence of the long-term exposure to tartrazine and chlorophyll on the fibrogenic signalling pathway in liver and kidney of rats: the expression patterns of collagen 1-α …

YM Abd-Elhakim, GG Moustafa, MM Hashem… - … Science and Pollution …, 2019 - Springer
Colouring agents are highly present in diverse products in the human environment. We
aimed to elucidate the fibrogenic cascade triggered by the food dyes tartrazine and …

Combine colorants of tartrazine and erythrosine induce kidney injury: involvement of TNF-α gene, caspase-9 and KIM-1 gene expression and kidney functions indices

W Iheanyichukwu, AO Adegoke… - Toxicology …, 2021 - Taylor & Francis
Twenty-five male Wistar rats (140–170 g) were partitioned into 5 groups (n= 5). 2.5 mg/kg, 5
mg/kg, 10 mg/kg and 20 mg/kg of combine Tartrazine and Erythrosine (T+ E; 50: 50) were …

[PDF][PDF] Toxicity induced after subchronic administration of the synthetic food dye tartrazine in adult rats, role of oxidative stress

N El Golli - Recent Adv Biol Med, 2016 - researchgate.net
The present study was conducted to evaluate the toxic potential of tartrazine, a food color, in
different tissues in adult rat: blood, liver, kidneys, and spleen. Tartrazine was administered …

Effect of resveratrol on tubular damage and interstitial fibrosis in kidneys of rats exposed to cigarette smoke

M Kuruş, M Ugras, M Esrefoglu - Toxicology and industrial …, 2009 - journals.sagepub.com
The aim of this study was to evaluate the effect of resveratrol on kidney tissue of rats
exposed to cigarette smoke. Forty adult male Wistar Albino rats were divided into four …

[HTML][HTML] Tartrazine induces structural and functional aberrations and genotoxic effects in vivo

L Khayyat, A Essawy, J Sorour, A Soffar - PeerJ, 2017 - peerj.com
Tartrazine is a synthetic organic azo dye widely used in food and pharmaceutical products.
The current study aimed to evaluate the possible adverse effect of this coloring food additive …

Resveratrol alleviates pyraclostrobin-induced lipid peroxidation, oxidative stress, and DNA damage in rats

F Zemheri-Navruz, S Ince, D Arslan-Acaroz… - … Science and Pollution …, 2023 - Springer
Pyraclostrobin (Pyra) is a fungicide in the strobilurin class and has proven to be very toxic to
organisms primarily aquatic species. Resveratrol (Res) is a phytoalexin that exhibits multiple …

[HTML][HTML] Proanthocyanidins attenuated liver damage and suppressed fibrosis in CCl4-treated rats

MA Amer, AI Othman, MA El-Missiry, AA Farag… - … Science and Pollution …, 2022 - Springer
Liver damage and fibrosis are serious health problems without effective treatment.
Proanthocyanidins (PAs) are flavonoids with several biological effects. We investigated the …

Melatonin ameliorates carbon tetrachloride-induced hepatic fibrogenesis in rats via inhibition of oxidative stress

H Wang, W Wei, NP Wang, SY Gui, L Wu, WY Sun… - Life sciences, 2005 - Elsevier
Melatonin is reported to exhibit a wide variety of biological effects, including antioxidant and
anti-inflammatory. Evidence shows the important role of oxidative stress in the …

Toxic effect of synthetic and natural food dyes on renal and hepatic functions in rats

HA Mekkawy, MO Ali, AM El-Zawahry - Toxicology Letters, 1998 - elibrary.ru
Evaluation of the toxic effects of synthetic dyes (ponceau, carmoisine, erythrosine, sunset
yellow, tartrazine, fast green, indigotine, brilliant blue and brilliant black) and natural dyes …

Resveratrol reverses thioacetamide‐induced renal assault with respect to oxidative stress, renal function, DNA damage, and cytokine release in Wistar rats

S Zargar, M Alonazi, H Rizwana… - Oxidative medicine and …, 2019 - Wiley Online Library
Background. Thioacetamide (TAA), a class 2B‐type carcinogen, is a potent toxicant.
Toxicities caused by this compound in various tissues due to oxidative stress, increase of …