[HTML][HTML] Global adoption of single-shot targeted intraoperative radiotherapy (TARGIT-IORT) for breast cancer—better for patients, better for healthcare systems

JS Vaidya, UJ Vaidya, M Baum, MK Bulsara… - Frontiers in …, 2022 - frontiersin.org
Micro abstract Targeted intraoperative radiotherapy (TARGIT-IORT) is delivered immediately
after lumpectomy for breast cancer. We estimated its impact. At least 44,752 patients with …

Environmental and social benefits of the targeted intraoperative radiotherapy for breast cancer: data from UK TARGIT-A trial centres and two UK NHS hospitals …

NJ Coombs, JM Coombs, UJ Vaidya, J Singer… - BMJ open, 2016 - bmjopen.bmj.com
Objective To quantify the journeys and CO2 emissions if women with breast cancer are
treated with risk-adapted single-dose targeted intraoperative radiotherapy (TARGIT) rather …

The TARGIT-A randomized trial: TARGIT-IORT versus whole breast radiation therapy: long-term local control and survival

JS Vaidya, M Bulsara, F Wenz, E Sperk… - International journal of …, 2023 - redjournal.org
Single-dose targeted intraoperative radiation therapy (TARGIT-IORT) during lumpectomy for
patients with early breast cancer can avoid the inconvenience and toxicity of whole breast …

Long term survival and local control outcomes from single dose targeted intraoperative radiotherapy during lumpectomy (TARGIT-IORT) for early breast cancer …

JS Vaidya, M Bulsara, M Baum, F Wenz, S Massarut… - bmj, 2020 - bmj.com
Objective To determine whether risk adapted intraoperative radiotherapy, delivered as a
single dose during lumpectomy, can effectively replace postoperative whole breast external …

[HTML][HTML] An international randomised controlled trial to compare TARGeted Intraoperative radioTherapy (TARGIT) with conventional postoperative radiotherapy after …

JS Vaidya, F Wenz, M Bulsara, JS Tobias… - Health Technology …, 2016 - ncbi.nlm.nih.gov
BACKGROUND Based on our laboratory work and clinical trials we hypothesised that
radiotherapy after lumpectomy for breast cancer could be restricted to the tumour bed. In …

[HTML][HTML] Single-dose intraoperative radiotherapy during lumpectomy for breast cancer: an innovative patient-centred treatment

JS Vaidya, M Bulsara, M Baum, JS Tobias - British journal of cancer, 2021 - nature.com
In the randomised TARGIT-A trial, risk-adapted targeted intraoperative radiotherapy
(TARGIT-IORT) during lumpectomy was non-inferior to whole-breast external beam …

[HTML][HTML] New clinical and biological insights from the international TARGIT-A randomised trial of targeted intraoperative radiotherapy during lumpectomy for breast …

JS Vaidya, M Bulsara, M Baum, F Wenz… - British journal of …, 2021 - nature.com
Abstract Background The TARGIT-A trial reported risk-adapted targeted intraoperative
radiotherapy (TARGIT-IORT) during lumpectomy for breast cancer to be as effective as …

[HTML][HTML] Risk-adapted targeted intraoperative radiotherapy versus whole-breast radiotherapy for breast cancer: 5-year results for local control and overall survival from …

JS Vaidya, F Wenz, M Bulsara, JS Tobias, DJ Joseph… - The Lancet, 2014 - thelancet.com
Summary Background The TARGIT-A trial compared risk-adapted radiotherapy using single-
dose targeted intraoperative radiotherapy (TARGIT) versus fractionated external beam …

[HTML][HTML] Eligibility criteria for intraoperative radiotherapy for breast cancer: study employing 12,025 patients treated in two cohorts

A Ziouèche-Mottet, G Houvenaeghel, JM Classe… - BMC cancer, 2014 - Springer
Background We wished to estimate the proportion of patients with breast cancer eligible for
an exclusive targeted intraoperative radiotherapy (TARGIT) and to evaluate their survival …

[HTML][HTML] Intraoperative radiotherapy for breast cancer: powerful evidence to change practice

JS Vaidya, M Bulsara, M Baum, M Alvarado… - Nature reviews Clinical …, 2021 - nature.com
2. Vaidya, JS et al. Long term survival and local control outcomes from single dose targeted
intraoperative radiotherapy during lumpectomy (TARGIT-IORT) for early breast cancer …