How viral and intracellular bacterial pathogens reprogram the metabolism of host cells to allow their intracellular replication

W Eisenreich, T Rudel, J Heesemann… - Frontiers in cellular and …, 2019 - frontiersin.org
Viruses and intracellular bacterial pathogens (IBPs) have in common the need of suitable
host cells for efficient replication and proliferation during infection. In human infections, the …

Hijacking the supplies: metabolism as a novel facet of virus-host interaction

KA Mayer, J Stöckl, GJ Zlabinger… - Frontiers in …, 2019 - frontiersin.org
Viral replication is a process that involves an extremely high turnover of cellular molecules.
Since viruses depend on the host cell to obtain the macromolecules needed for their proper …

Virus control of cell metabolism for replication and evasion of host immune responses

MMB Moreno-Altamirano, SE Kolstoe… - Frontiers in cellular …, 2019 - frontiersin.org
Over the last decade, there has been significant advances in the understanding of the cross-
talk between metabolism and immune responses. It is now evident that immune cell effector …

Stealing the keys to the kitchen: viral manipulation of the host cell metabolic network

CM Goodwin, S Xu, J Munger - Trends in microbiology, 2015 - cell.com
Host cells possess the metabolic assets required for viral infection. Recent studies indicate
that control of the host's metabolic resources is a core host–pathogen interaction. Viruses …

Hostile takeover: how viruses reprogram prokaryotic metabolism

TB Jacobson, MM Callaghan… - Annual Review of …, 2021 - annualreviews.org
To reproduce, prokaryotic viruses must hijack the cellular machinery of their hosts and
redirect it toward the production of viral particles. While takeover of the host replication and …

Metabolic host responses to infection by intracellular bacterial pathogens

W Eisenreich, J Heesemann, T Rudel… - Frontiers in cellular and …, 2013 - frontiersin.org
The interaction of bacterial pathogens with mammalian hosts leads to a variety of
physiological responses of the interacting partners aimed at an adaptation to the new …

[HTML][HTML] Viral activation of cellular metabolism

EL Sanchez, M Lagunoff - Virology, 2015 - Elsevier
To ensure optimal environments for their replication and spread, viruses have evolved to
alter many host cell pathways. In the last decade, metabolomic studies have shown that …

Virus infections and host metabolism—can we manage the interactions?

D Sumbria, E Berber, M Mathayan… - Frontiers in …, 2021 - frontiersin.org
When viruses infect cells, they almost invariably cause metabolic changes in the infected
cell as well as in several host cell types that react to the infection. Such metabolic changes …

Intracellular pathogens: host immunity and microbial persistence strategies

A Thakur, H Mikkelsen… - Journal of immunology …, 2019 - Wiley Online Library
Infectious diseases caused by pathogens including viruses, bacteria, fungi, and parasites
are ranked as the second leading cause of death worldwide by the World Health …

Monocytes and macrophages as viral targets and reservoirs

E Nikitina, I Larionova, E Choinzonov… - International journal of …, 2018 - mdpi.com
Viruses manipulate cell biology to utilize monocytes/macrophages as vessels for
dissemination, long-term persistence within tissues and virus replication. Viruses enter cells …