[HTML][HTML] Hesperidin prevents retinal and plasma abnormalities in streptozotocin-induced diabetic rats

X Shi, S Liao, H Mi, C Guo, D Qi, F Li, C Zhang, Z Yang - Molecules, 2012 - mdpi.com
Diabetic retinopathy is a complex disease that potentially involves increased production of
advanced glycosylation end products (AGEs) and elevated aldose reductase (AR) activity …

Hesperetin rescues retinal oxidative stress, neuroinflammation and apoptosis in diabetic rats

B Kumar, SK Gupta, BP Srinivasan, TC Nag… - Microvascular …, 2013 - Elsevier
The purpose of the study was to evaluate the effects of hesperetin (Hsp) on diabetes-
induced retinal oxidative stress, neuroinflammation and apoptosis in rats. The Hsp treatment …

Eriodictyol prevents early retinal and plasma abnormalities in streptozotocin-induced diabetic rats

C Bucolo, GM Leggio, F Drago, S Salomone - Biochemical pharmacology, 2012 - Elsevier
Diabetic retinopathy is a complex disease that has potential involvement of inflammatory
and oxidative stress-related pathways in its pathogenesis. We hypothesized that eriodictyol …

[HTML][HTML] Flavonoid naringenin attenuates oxidative stress, apoptosis and improves neurotrophic effects in the diabetic rat retina

DI Al-Dosari, MM Ahmed, SS Al-Rejaie, AS Alhomida… - Nutrients, 2017 - mdpi.com
Diabetic retinopathy (DR) is one of the leading causes of decreased vision and blindness
worldwide. Diabetes-induced oxidative stress is believed to be the key factor that initiates …

[HTML][HTML] Grape seed proanthocyanidin extract protects the retina against early diabetic injury by activating the Nrf2 pathway

Y Sun, C Xiu, W Liu, Y Tao… - Experimental and …, 2016 - spandidos-publications.com
The present study aimed to investigate whether grape seed proanthocyanidin extract
(GSPE) has a protective effect on diabetic retinal function. A total of 30 Wistar rats were …

Hesperetin ameliorates hyperglycemia induced retinal vasculopathy via anti-angiogenic effects in experimental diabetic rats

B Kumar, SK Gupta, BP Srinivasan, TC Nag… - Vascular …, 2012 - Elsevier
The purpose of the study was to evaluate vasculoprotective effects of Hesperetin (Hsp) in
Streptozotocin induced diabetic rats. The study was carried out for a period of 24weeks and …

[HTML][HTML] Puerarin prevents cataract development and progression in diabetic rats through Nrf2/HO‑1 signaling

D Zhang, M Li - Molecular Medicine Reports, 2019 - spandidos-publications.com
Puerarin is the major bioactive ingredient isolated from the dry root of Pueraria lobata, a
plant used in traditional Chinese medicine. Puerarin has been used to treat diabetes and …

[HTML][HTML] Silymarin reduces retinal microvascular damage in streptozotocin-induced diabetic rats

R Karimi, A Bakhshi, P Dayati, O Abazari, M Shahidi… - Scientific Reports, 2022 - nature.com
Diabetic retinopathy is a severe microvascular problem in diabetes mellitus. Silymarin is a
flavonoid compound, and according to previous studies, it is a bioactive compound with …

[HTML][HTML] Quercetin protects against diabetic retinopathy in rats by inducing heme oxygenase-1 expression

GR Chai, S Liu, HW Yang, XL Chen - Neural Regeneration …, 2021 - journals.lww.com
Quercetin is a widely-occurring flavonoid that protects against cancer, and improves memory
and cardiovascular functions. However, whether quercetin exhibits therapeutic effects in …

[HTML][HTML] Zerumbone, a bioactive sesquiterpene, ameliorates diabetes-induced retinal microvascular damage through inhibition of phospho-p38 mitogen-activated …

WY Liu, TF Tzeng, IM Liu - Molecules, 2016 - mdpi.com
Zerumbone ameliorates retinal damage by blocking advanced glycation end products and
their receptor system in streptozotocin-diabetic rats. Because of the multiple factors involved …