The etiology of hypertension historically includes 2 components: genetics and lifestyle.
However, recent epidemiologic studies report an inverse relationship between birth weight …

Hypertension (HTN) and chronic kidney disease are highly prevalent diseases that tend to
occur more frequently among disadvantaged populations, in whom prenatal care also tends …

Events that occur in the early fetal environment have been linked to long‐term health and
lifespan consequences in the adult. Intrauterine growth restriction (IUGR), which may occur …

Epidemiologic studies from several different populations have demonstrated that prenatal
insults, which adversely affect fetal growth, result in an increased incidence of hypertension …

The concept of developmental origins of adult diseases derives from several different types
of observations. The thought that there were critical or ''sensitive''periods of development …

A growing body of evidence supports the concept that changes in the intrauterine milieu
during “sensitive” periods of embryonic development or in infant diet after birth affect the …

As discussed elsewhere in this issue, beginning with David Barker's insight and original
observations leading to the Fetal Origins of Adult Disease hypothesis (1), epidemiologic …

The concept of fetal programming of disease in later life after intrauterine growth restriction
(IUGR) has opened a potential new perspective on the treatment and prevention of arterial …

Nutritional and other environmental cues during development can permanently alter the
structure, homeostatic systems, and functions of the body. This phenomenon has been …

Impaired intrauterine nephrogenesis—most clearly illustrated by low nephron number—is
frequently associated with low birthweight and has been recognized as a powerful risk factor …