Relationship of autoantibodies to MDA-LDL and ApoB-immune complexes to sex, ethnicity, subclinical atherosclerosis, and cardiovascular events
A Prasad, P Clopton, C Ayers, A Khera… - … , and vascular biology, 2017 - Am Heart Assoc
Objective—Modifications of lipid constituents within atherosclerotic lesions generate
neoepitopes that activate innate and adaptive immune responses. We aimed to define the …
neoepitopes that activate innate and adaptive immune responses. We aimed to define the …
Relationship of IgG and IgM autoantibodies to oxidized low density lipoprotein with coronary artery disease and cardiovascular events
S Tsimikas, ES Brilakis, RJ Lennon, ER Miller… - Journal of lipid …, 2007 - ASBMB
The relationship between autoantibodies to oxidized low density lipoprotein (OxLDL) and
coronary artery disease (CAD) remains controversial. IgM and IgG OxLDL autoantibodies to …
coronary artery disease (CAD) remains controversial. IgM and IgG OxLDL autoantibodies to …
Immunoglobulin M type of autoantibodies to oxidized low-density lipoprotein has an inverse relation to carotid artery atherosclerosis
J Karvonen, M Päivänsalo, YA Kesäniemi… - Circulation, 2003 - Am Heart Assoc
Background—Lipoprotein oxidation plays an important part in atherogenesis.
Autoantibodies to oxidation-specific epitopes of LDL occur in plasma and atherosclerotic …
Autoantibodies to oxidation-specific epitopes of LDL occur in plasma and atherosclerotic …
LDL immunization induces T-cell–dependent antibody formation and protection against atherosclerosis
X Zhou, G Caligiuri, A Hamsten, AK Lefvert… - … , and vascular biology, 2001 - Am Heart Assoc
Atherosclerosis is an inflammatory disease, and the involvement of immune mechanisms in
disease progression is increasingly recognized. Immunization with oxidized low density …
disease progression is increasingly recognized. Immunization with oxidized low density …
Is atherosclerosis an autoimmune disease?
E Matsuura, F Atzeni, P Sarzi-Puttini, M Turiel… - BMC medicine, 2014 - Springer
Immunologic research into pathogenic mechanisms operating in autoimmune-mediated
atherosclerosis initially focused on adaptive immunity. Current interest is directed to more …
atherosclerosis initially focused on adaptive immunity. Current interest is directed to more …
Autoantibodies against MDA-LDL in subjects with severe and minor atherosclerosis and healthy population controls
LPL van de Vijver, R Steyger, G van Poppel, JMA Boer… - Atherosclerosis, 1996 - Elsevier
Autoantibodies against oxidized low-density lipoprotein (LDL) have been reported to be
associated with atherosclerosis. However, data are not consistent. We compared the titres of …
associated with atherosclerosis. However, data are not consistent. We compared the titres of …
Relationship of IgG and IgM autoantibodies and immune complexes to oxidized LDL with markers of oxidation and inflammation and cardiovascular events: results …
Levels of IgG and IgM autoantibodies (AA) to malondialdehyde (MDA)-LDL and apoB-
immune complexes (ICs) were measured in 748 cases and 1,723 controls in the EPIC …
immune complexes (ICs) were measured in 748 cases and 1,723 controls in the EPIC …
Circulating autoantibodies against the apolipoprotein B-100 peptides p45 and p210 in relation to the occurrence of carotid plaques in 64-year-old women
B Fagerberg, U Prahl Gullberg, R Alm, J Nilsson… - PloS one, 2015 - journals.plos.org
Objectives Immune responses against oxidized low density lipoprotein (LDL) play a key role
in atherosclerosis. Previous studies have indicated inverse associations between …
in atherosclerosis. Previous studies have indicated inverse associations between …
Pathogenic role of modified LDL antibodies and immune complexes in atherosclerosis
MF Lopes-Virella, G Virella - Journal of Atherosclerosis and …, 2013 - jstage.jst.go.jp
Chronic inflammation is believed to be a major, if not the major, pathogenic factor in human
atherosclerosis1, 2). Both innate and adaptive responses have been proposed to play a role …
atherosclerosis1, 2). Both innate and adaptive responses have been proposed to play a role …
Human-derived anti-oxidized LDL autoantibody blocks uptake of oxidized LDL by macrophages and localizes to atherosclerotic lesions in vivo
PX Shaw, S Hörkkö, S Tsimikas… - … , and vascular biology, 2001 - Am Heart Assoc
Autoantibodies to oxidation-specific epitopes of low density lipoprotein (LDL), such as
malondialdehyde-modified LDL (MDA-LDL), occur in plasma and atherosclerotic lesions of …
malondialdehyde-modified LDL (MDA-LDL), occur in plasma and atherosclerotic lesions of …
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