Evolution of Streptococcus pneumoniae and Its Close Commensal Relatives

M Kilian, K Poulsen, T Blomqvist, LS Håvarstein… - PloS one, 2008 - journals.plos.org
Streptococcus pneumoniae is a member of the Mitis group of streptococci which, according
to 16S rRNA-sequence based phylogenetic reconstruction, includes 12 species. While other …

Identification of virulence-associated properties by comparative genome analysis of Streptococcus pneumoniae, S. pseudopneumoniae, S. mitis, three S. oralis …

M Kilian, H Tettelin - MBio, 2019 - Am Soc Microbiol
From a common ancestor, Streptococcus pneumoniae and Streptococcus mitis evolved in
parallel into one of the most important pathogens and a mutualistic colonizer of humans …

Novel molecular method for identification of Streptococcus pneumoniae applicable to clinical microbiology and 16S rRNA sequence-based microbiome studies

CFP Scholz, K Poulsen, M Kilian - Journal of clinical microbiology, 2012 - Am Soc Microbiol
The close phylogenetic relationship of the important pathogen Streptococcus pneumoniae
and several species of commensal streptococci, particularly Streptococcus mitis and …

Parallel evolution of Streptococcus pneumoniae and Streptococcus mitis to pathogenic and mutualistic lifestyles

M Kilian, DR Riley, A Jensen, H Brüggemann… - MBio, 2014 - Am Soc Microbiol
The bacterium Streptococcus pneumoniae is one of the leading causes of fatal infections
affecting humans. Intriguingly, phylogenetic analysis shows that the species constitutes one …

The Genome of Streptococcus mitis B6 - What Is a Commensal?

D Denapaite, R Brückner, M Nuhn, P Reichmann… - PloS one, 2010 - journals.plos.org
Streptococcus mitis is the closest relative of the major human pathogen S. pneumoniae. The
2, 15 Mb sequence of the Streptococcus mitis B6 chromosome, an unusually high-level beta …

Genetic Relationships between Clinical Isolates of Streptococcus pneumoniae, Streptococcus oralis, and Streptococcus mitis: Characterization of “Atypical” Pneumococci and Organisms …

AM Whatmore, A Efstratiou, AP Pickerill… - Infection and …, 2000 - Am Soc Microbiol
The oral streptococcal group (mitis phylogenetic group) currently consists of nine recognized
species, although the group has been traditionally difficult to classify, with frequent changes …

Comparative Genomics of the Bacterial Genus Streptococcus Illuminates Evolutionary Implications of Species Groups

XY Gao, XY Zhi, HW Li, HP Klenk, WJ Li - PloS one, 2014 - journals.plos.org
Members of the genus Streptococcus within the phylum Firmicutes are among the most
diverse and significant zoonotic pathogens. This genus has gone through considerable …

Identification of Streptococcus pneumoniae and other Mitis streptococci: importance of molecular methods

E Sadowy, W Hryniewicz - European Journal of Clinical Microbiology & …, 2020 - Springer
The Mitis group of streptococci includes an important human pathogen, Streptococcus
pneumoniae (pneumococcus) and about 20 other related species with much lower …

Robust demarcation of fourteen different species groups within the genus Streptococcus based on genome-based phylogenies and molecular signatures

S Patel, RS Gupta - Infection, Genetics and Evolution, 2018 - Elsevier
The genus Streptococcus comprises many important pathogens that impact human and
animal health. Despite their widespread relevance, accurate classification and methods to …

Structure and dynamics of the pan-genome of Streptococcus pneumoniae and closely related species

C Donati, NL Hiller, H Tettelin, A Muzzi, NJ Croucher… - Genome biology, 2010 - Springer
Background Streptococcus pneumoniae is one of the most important causes of microbial
diseases in humans. The genomes of 44 diverse strains of S. pneumoniae were analyzed …