Cigarette smoking is the most prevalent risk factor for the development of adult-onset
respiratory diseases associated with airflow obstruction, namely emphysema and chronic …

In developed countries approximately one-quarter of adults with asthma are active cigarette
smokers. These individuals have poorly controlled symptoms, impaired therapeutic …

Chronic obstructive pulmonary disease (COPD) is part of a worldwide tobacco-related
disease epidemic, and is associated with progressive airflow obstruction and varying …

Background: Irreversible airways obstruction in smokers is usually attributed to chronic
obstructive pulmonary disease (COPD). We speculate that some of these are cases of …

COPD is a complex inflammatory disease that involves multiple interacting cells and
mediators and various tissue destruction and repair mechanisms leading to structural …

Until recently, the conceptual model of the natural history of COPD has been greatly focused
on an accelerated decline of lung function, which would occur in adult life in susceptible …

The aim of the present study was to analyse the interaction between asthma and smoking in
the risk of adult airway obstruction, accounting for atopy. In the European Community …

Patients with concomitant features of asthma and chronic obstructive pulmonary disease
(COPD) have a heavy disease burden. Using data collected prospectively in the European …

Expiratory Volume in 1st second (FEV1) decline over about two decades. It shed light for the
first time that lung function trajectories may follow different paths leading to COPD. Half of …

Little is known about chronic obstructive pulmonary disease (COPD) in Chinese
nonsmokers. The present study aimed to investigate the profiles of COPD among …