Representation and control of pain and itch by distinct prefrontal neural ensembles
Pain and itch are two closely related but essentially distinct sensations that elicit different
behavioral responses. However, it remains mysterious how pain and itch information is …
behavioral responses. However, it remains mysterious how pain and itch information is …
[HTML][HTML] Distinct brain systems mediate the effects of nociceptive input and self-regulation on pain
Cognitive self-regulation can strongly modulate pain and emotion. However, it is unclear
whether self-regulation primarily influences primary nociceptive and affective processes or …
whether self-regulation primarily influences primary nociceptive and affective processes or …
[HTML][HTML] Central medial thalamic nucleus dynamically participates in acute itch sensation and chronic itch-induced anxiety-like behavior in male mice
JN Li, XM Wu, LJ Zhao, HX Sun, J Hong, FL Wu… - Nature …, 2023 - nature.com
Itch is an annoying sensation consisting of both sensory and emotional components. It is
known to involve the parabrachial nucleus (PBN), but the following transmission nodes …
known to involve the parabrachial nucleus (PBN), but the following transmission nodes …
Brain mechanisms supporting discrimination of sensory features of pain: a new model
Y Oshiro, AS Quevedo, JG McHaffie… - Journal of …, 2009 - Soc Neuroscience
Pain can be very intense or only mild, and can be well localized or diffuse. To date, little is
known as to how such distinct sensory aspects of noxious stimuli are processed by the …
known as to how such distinct sensory aspects of noxious stimuli are processed by the …
Multiplexed representation of itch and mechanical and thermal sensation in the primary somatosensory cortex
The primary somatosensory cortex (S1) plays a critical role in processing multiple
somatosensations, but the mechanism underlying the representation of different …
somatosensations, but the mechanism underlying the representation of different …
[PDF][PDF] Disrupted population coding in the prefrontal cortex underlies pain aversion
The prefrontal cortex (PFC) regulates a wide range of sensory experiences. Chronic pain is
known to impair normal neural response, leading to enhanced aversion. However, it …
known to impair normal neural response, leading to enhanced aversion. However, it …
An amygdalar neural ensemble that encodes the unpleasantness of pain
Pain is an unpleasant experience. How the brain's affective neural circuits attribute this
aversive quality to nociceptive information remains unknown. By means of time-lapse in vivo …
aversive quality to nociceptive information remains unknown. By means of time-lapse in vivo …
Pain-preferential thalamocortical neural dynamics across species
Searching for pain-preferential neural activity is essential for understanding and managing
pain. Here, we investigated the preferential role of thalamocortical neural dynamics in …
pain. Here, we investigated the preferential role of thalamocortical neural dynamics in …
[PDF][PDF] A nociceptive neuronal ensemble in the dorsomedial prefrontal cortex underlies pain chronicity
Pain chronicity involves unpleasant experience in both somatosensory and affective
aspects, accompanied with the prefrontal cortex (PFC) neuroplastic alterations. However …
aspects, accompanied with the prefrontal cortex (PFC) neuroplastic alterations. However …
Your pain or mine? Common and distinct neural systems supporting the perception of pain in self and other
KN Ochsner, J Zaki, J Hanelin… - Social cognitive and …, 2008 - academic.oup.com
Humans possess a remarkable capacity to understand the suffering of others. Cognitive
neuroscience theories of empathy suggest that this capacity is supported by 'shared …
neuroscience theories of empathy suggest that this capacity is supported by 'shared …