The Hippo/YAP signaling pathway is important for mediating organ size and tissue
homeostasis, but its role in osteoarthritis (OA) remains unclear. We aimed to investigate the …

The Hippo/yes-associated protein 1 signaling pathway is an evolutionarily conserved
signaling pathway. This signaling pathway is primarily involved in the regulation of stem cell …

Osteoarthritis (OA) is an age-related disease, characterized by cartilage degeneration. The
pathogenesis of OA is complicated and the current therapeutic approaches for OA are …

Disc herniation is a kind of disease caused by degenerative discs, which is common in the
elderly, bringing substantial financial burden to families and society. Mechanical tension has …

Abstract YAP1 (Yes-associated protein 1) transcriptional coactivator is a downstream gene
of the Hippo signaling pathway, which controls cell proliferation and differentiation. YAP1 …

Hippo signaling controls organ size and tissue regeneration in many organs, but its roles in
chondrocyte differentiation and bone repair remain elusive. Here, we demonstrate that …

Abstract Yes‐associated protein 1 (YAP1), the core downstream effector of the Hippo
signaling cascade, was involved in the regulation of osteoblast and osteoclast differentiation …

Abstract Yes-associated protein 1 (YAP1), the core effector of the Hippo signaling pathway,
has been identified as a key regulator of tissue homeostasis and organ development by …

Osteoarthritis (OA) constitutes the most common disease of degenerative joints, with
chondrocytes playing an important role in disease progression. However, the underlying …

Osteoarthritis (OA) is a widespread degenerative joint disease that affects more than 350
million people worldwide. Although YAP1 has been proved to play a key role in OA, the …