Dirofilaria immitis carries intracellular endosymbiotic bacteria of the genus Wolbachia,
known to be vital for the worms and sensitive to tetracycline antibiotics. With the purpose of …

Since the definitive identification in 1995 of the bacterial endosymbiont Wolbachia that
resides in different tissues of the filarial worm Dirofilaria immitis, there has been increasing …

Bacteria of the genus Wolbachia are endosymbionts of parasitic filarial nematodes,
including Dirofilaria immitis, and are a target for the treatment of canine heartworm disease …

Tetracycline treatment of animals or humans infected with filariae that harbor Wolbachia
endosymbionts blocks further embryogenesis, and existing microfilariae gradually die. This …

Dirofilaria immitis is the causative agent of heartworm disease in canines and felines, and
pulmonary dirofilariasis in man. It harbors a symbiotic intracellular bacterium from the genus …

The endosymbiont bacteria Wolbachia plays an important role in the pathogenesis and
inflammatory immune response to heartworm (Dirofilaria immitis) infection in dogs …

Heartworm disease caused by Dirofilaria immitis affects canine and feline hosts, with
infections occasionally being reported in humans. Studies have shown that both dirofilarial …

Dirofilaria immitis is the causative agent of canine and feline heartworm disease. Adult
worms live in the pulmonary arteries, females produce firststage larvae (“microfilariae”) …

Sera from Dirofilaria immitis-experimentally infected dogs treated with a combination of
ivermectin/doxycycline were analysed for doxycycline levels by HPLC and anti-Wolbachia …

Wolbachia pipiens, an intracellular endosymbiont bacteria of filarial nematodes, has been
implicated in the pathogenesis of filarial diseases, in particular in heavy Dirofilaria spp …