Sleep-immune interactions are well-known phenomena in everyday life and folk wisdom.
There is no doubt that an infection makes us tired and increases the desire to sleep, and a …

For millennia individuals have known that sleep is altered during sickness, and indeed many
follow the advice to get sleep as an aid for recuperation from disease states. Hippocrates …

Sleep is a fundamental biological need in humans. Sleep deprivation from medical and
psychiatric conditions, as well as from life style (eg shift work, jet lag) is endemic in modern …

A reduction in the amount of time spent sleeping occurs chronically in modern society.
Clinical and experimental studies in humans and animal models have shown that immune …

Recent animal and human studies show that the immune-neuroendocrine-thermal
operations of the body are intimately linked to the sleeping-waking brain. In humans, the …

Sleep is considered an important modulator of the immune response. Thus, a lack of sleep
can weaken immunity, increasing organism susceptibility to infection. For instance, shorter …

The complex and intimate interactions between the sleep and immune systems have been
the focus of study for several years. Immune factors, particularly the interleukins, regulate …

Research models show a strong interrelationship between sleep quality and immune
function. The proinflammatory cytokines, interleukin-1, interleukin-6, and tumor necrosis …

In the last twenty years we have realized that the immune system synthesizes a class of
peptides, termed cytokines, that play a central role in alerting the brain to ongoing …

It is a common belief that we are more susceptible to infections when deprived of sleep.
Consistent with this, there is increasing evidence that sleep deprivation has detrimental …