Sleep is vital to health and quality of life while sleep abnormalities are associated with
adverse health consequences. Nevertheless, sleep problems are not generally considered …

Scientists are only beginning to fully understand the purpose of sleep and its underlying
mechanisms. Lack of sleep is associated with many diseases, including infection, and with …

The effect of 40 h of wakefulness on a variety of immunological parameters in the peripheral
blood from 10 normal male subjects was studied. Sleep deprivation led to enhanced …

This review describes mechanisms of immune-to-brain and brain-to-immune signaling
involved in mediating physiological sleep and altered sleep with disease. The central …

A joint function of tissues, organs and cells for the protection of body develops immune
system. The human immune response against various infections during sleep, its …

The specific systems and mechanisms affected by sleep deprivation that may perpetuate
disease processes in humans still are speculative. In laboratory rats, prolonged sleep …

Excessive sleepiness and fever are constitutional symptoms associated with systemic
infection. Although fevers have been investigated for many years, sleep responses to …

Conclusions Sleep can clearly be modulated by exogenous administration of cytokines, and
is also likely to be regulated, in part, by endogenous cytokines. The synthesis of small …

Personal experience and empirical data indicate sleep is altered during sickness. Important
signaling molecules of the peripheral immune system called cytokines orchestrate …

The restorative functions of sleep may affect immunologic functioning. The present study
examined the effects of sleep on stimulated cytokine release in 13 healthy men. The …