Sleep is a vital phenomenon related to immunomodulation at the central and peripheral
level. Sleep deficient in duration and/or quality is a common problem in the modern society …

Infectious challenges induce sleep responses in the host characterized by an increase in
non-rapid eye movement sleep (NREMS) followed by a period of decreased NREMS. Such …

Interleukin-1 beta (IL1) and tumor necrosis factor alpha (TNF) promote non-rapid eye
movement sleep under physiological and inflammatory conditions. Additional cytokines are …

Sleep is an important component of mammalian homeostasis, vital for the survival of self and
species. People spend at least one third of their lives asleep, yet have little understanding of …

Objective The goal of this study was to investigate whether clinical insomnia is associated
with immune alterations by comparing immune functioning between patients with chronic …

Sleep disturbance is associated with inflammation and related disorders including
cardiovascular disease, arthritis, and diabetes mellitus. Given sex differences in the …

Sleepiness is a common complaint during infectious diseases, but the interaction between
sleep and host defense mechanisms has been poorly explored in humans. We therefore …

Abstract Study Objectives: There is evidence that sleep facilitates the adaptive immune
response to infectious agents and, thereby, supports immunologic memory. The effect might …

Sleep deprivation disrupts vital biological processes that are necessary for cognitive ability
and physical health, but the physiological changes that underlie these outward effects are …

Sleep regulates immune functions. We asked whether sleep can influence immunological
memory formation. Twenty-seven healthy men were vaccinated against hepatitis A three …