Small angle X-ray diffraction as a tool for structural characterization of muscle disease

W Ma, TC Irving - International Journal of Molecular Sciences, 2022 - mdpi.com
Small angle X-ray fiber diffraction is the method of choice for obtaining molecular level
structural information from striated muscle fibers under hydrated physiological conditions …

[PDF][PDF] Direct modeling of x-ray diffraction pattern from skeletal muscle in rigor

NA Koubassova, AK Tsaturyan - Biophysical journal, 2002 - cell.com
Available high-resolution structures of F-actin, myosin subfragment 1 (S1), and their
complex, actin-S1, were used to calculate a 2D x-ray diffraction pattern from skeletal muscle …

Recent improvements in small angle x-ray diffraction for the study of muscle physiology

M Reconditi - Reports on Progress in Physics, 2006 - iopscience.iop.org
The molecular mechanism of muscle contraction is one of the most important unresolved
problems in biology and biophysics. Notwithstanding the great advances of recent years, it is …

[PDF][PDF] Myofibril orientation as a metric for characterizing heart disease

W Ma, H Gong, V Jani, KH Lee, M Landim-Vieira… - Biophysical journal, 2022 - cell.com
Myocyte disarray is a hallmark of many cardiac disorders. However, the relationship
between alterations in the orientation of individual myofibrils and myofilaments to disease …

Interpretation of the X-ray diffraction pattern from relaxed skeletal muscle and modelling of the thick filament structure

SB Malinchik, VV Lednev - Journal of Muscle Research & Cell Motility, 1992 - Springer
The first part of this paper is devoted to the model-building studies of our high resolution
meridional X-ray diffraction patterns (in the region from 1/500 to 1/50 Å− 1) obtained from …

Recent x-ray diffraction studies of muscle

J Hanson - Quarterly reviews of biophysics, 1968 - cambridge.org
An intact living muscle has such a regular structure that it diffracts light or X-rays, thereby
providing patterns that contain uniquely valuable information. Interpretation of these patterns …

[HTML][HTML] Direct modeling of X-ray diffraction pattern from contracting skeletal muscle

NA Koubassova, SY Bershitsky, MA Ferenczi… - Biophysical …, 2008 - cell.com
A direct modeling approach was used to quantitatively interpret the two-dimensional x-ray
diffraction patterns obtained from contracting mammalian skeletal muscle. The dependence …

Time-resolved X-ray diffraction studies on vertebrate striated muscle

HE Huxley, AR Faruqi - Annual review of biophysics and …, 1983 - annualreviews.org
The purpose of the studies reviewed here has been to help to elucidate the molecular
mechanisms involved in muscular contraction. The structural basis of the contractile …

X-ray diffraction studies of the heart

I Matsubara - Annual Review of Biophysics and Bioengineering, 1980 - annualreviews.org
The contractile apparatus of vertebrate heart muscle is similar to that of vertebrate skeletal
muscle when viewed in the electron microscope (52, 61). The sarcomeres contain regular …

Myosin head configurations in resting and contracting murine skeletal muscle

W Ma, H Gong, T Irving - International journal of molecular sciences, 2018 - mdpi.com
Transgenic mouse models have been important tools for studying the relationship of
genotype to phenotype for human diseases, including those of skeletal muscle. We show …