Persistent organic pollutants in adipose tissue should be considered in obesity research

YM Lee, KS Kim, DR Jacobs Jr, DH Lee - Obesity Reviews, 2017 - Wiley Online Library
Although low doses of persistent organic pollutants (POPs), strong lipophilic chemicals with
long half‐lives, have been linked to various endocrine, immune, nervous and reproductive …

Increased blood levels of persistent organic pollutants (POP) in obese individuals after weight loss—A review

A Jansen, JL Lyche, A Polder, J Aaseth… - Journal of Toxicology …, 2017 - Taylor & Francis
Lipophilic persistent organic pollutants (POP) are stored in adipose tissue. Following rapid
weight loss such as when induced by bariatric surgery, an increased release of potential …

Toxicological function of adipose tissue: focus on persistent organic pollutants

M La Merrill, C Emond, MJ Kim… - Environmental …, 2013 - ehp.niehs.nih.gov
Background: Adipose tissue (AT) is involved in several physiological functions, including
metabolic regulation, energy storage, and endocrine functions. Objectives: In this review we …

[HTML][HTML] The role of persistent organic pollutants in obesity: a review of laboratory and epidemiological studies

J Aaseth, D Javorac, AB Djordjevic, Z Bulat, AV Skalny… - Toxics, 2022 - mdpi.com
Persistent organic pollutants (POPs) are considered as potential obesogens that may affect
adipose tissue development and functioning, thus promoting obesity. However, various …

[HTML][HTML] Persistent organic pollutants and type 2 diabetes: a critical review of review articles

YM Lee, DR Jacobs Jr, DH Lee - Frontiers in endocrinology, 2018 - frontiersin.org
Low dose persistent organic pollutants (POPs) have emerged as a new risk for type 2
diabetes (T2D). Despite substantial evidence from human and experimental studies, there …

Persistent organic pollutants as risk factors for obesity and diabetes

C Yang, APS Kong, Z Cai, ACK Chung - Current diabetes reports, 2017 - Springer
Purpose of review The rising prevalence of obesity and diabetes cannot be fully explained
by known risk factors, such as unhealthy diet, a sedentary lifestyle, and family history. This …

Persistent organic pollutants and adverse health effects in humans

Q Qing Li, A Loganath, Y Seng Chong… - Journal of Toxicology …, 2006 - Taylor & Francis
Persistent organic pollutants (POPs) are synthetic chemicals that have an intrinsic resistance
to natural degradation processes, and are therefore environmentally persistent. The …

Persistent organic pollutant levels in human visceral and subcutaneous adipose tissue in obese individuals—Depot differences and dysmetabolism implications

D Pestana, G Faria, C Sá, VC Fernandes… - Environmental …, 2014 - Elsevier
Background The role of persistent organic pollutants (POPs) with endocrine disrupting
activity in the aetiology of obesity and other metabolic dysfunctions has been recently …

Inverse associations between long-term weight change and serum concentrations of persistent organic pollutants

JS Lim, HK Son, SK Park, DR Jacobs… - International journal of …, 2011 - nature.com
There is emerging evidence that persistent organic pollutants (POPs) can increase the risk
of various chronic diseases. As POPs mainly bioaccumulate in adipose tissue, weight …

[HTML][HTML] Partitioning of persistent organic pollutants between adipose tissue and serum in human studies

MA Moriceau, G Cano-Sancho, MJ Kim, X Coumoul… - Toxics, 2022 - mdpi.com
Blood is the most widely used matrix for biomonitoring of persistent organic pollutants
(POPs). It is assumed that POPs are homogenously distributed within body lipids at steady …