Vaccination with circulating exosomes in autoimmune uveitis prevents recurrent intraocular inflammation

G Jiang, J Yun, HJ Kaplan, Y Zhao… - Clinical & …, 2021 - Wiley Online Library
Background Exosomes participate in intercellular communication and act as important
molecular vehicles in the regulation of numerous physiological and pathological processes …

Recent advances of exosomes in immune-mediated eye diseases

N Li, L Zhao, Y Wei, VL Ea, H Nian, R Wei - Stem cell research & therapy, 2019 - Springer
Exosomes, nanosized extracellular vesicles of 30–150 nm, are shed by almost all cell types.
Bearing proteins, lipids, RNAs, and DNAs, exosomes have emerged as vital biological …

Effects of mesenchymal stem cell-derived exosomes on experimental autoimmune uveitis

L Bai, H Shao, H Wang, Z Zhang, C Su, L Dong, B Yu… - Scientific reports, 2017 - nature.com
We previously demonstrated that mesenchymal stem cells (MSCs) ameliorated experimental
autoimmune uveoretinitis (EAU) in rats. Recently, MSC-derived exosomes (MSC-Exo) were …

Author correction: effects of mesenchymal stem cell-derived exosomes on experimental autoimmune uveitis

L Bai, H Shao, H Wang, Z Zhang, C Su, L Dong… - Scientific Reports, 2018 - nature.com
“Histological assessment of the retina in EAU. Sections of the retina were stained with
hematoxylin and eosin, and evaluated for histological damage on 15 and 20 days post …

Exosomes in the pathogenesis and treatment of ocular diseases

Z Zhang, X Liang, J Zhou, M Meng, Y Gao, G Yi… - Experimental Eye …, 2021 - Elsevier
Exosomes have diverse functions and rich content and are involved in intercellular
communication, immune regulation, viral infection, tissue regeneration, and the occurrence …

Isolation of rabbit aqueous humor-derived exosomes and their immunosuppression function

ZX Liao, ZQ Lou, Z Xiao - Zhejiang da xue xue bao. Yi xue ban …, 2012 - europepmc.org
Methods Aqueous humor was collected from 40 New Zealand rabbits and exosomes were
isolated by fractional separation and ultracentrifugation methods; the morphology was …

Circulating exosomes from patients with graves' disease induce an inflammatory immune response

X Cui, M Huang, S Wang, N Zhao, T Huang… - …, 2021 - academic.oup.com
Exosomes are extracellular vesicles that can participate in autoimmune diseases. The
purpose of this study was to explore whether circulating exosomes are involved in Graves' …

Topical ophthalmic instillation of engineered hMSCs-derived exosomes: a novel non-invasive therapeutic strategy for ocular posterior-segment disorder

H Yang, P Wu, T Wang, Y Yu, J Li, R Liu… - … and Biophysical Research …, 2024 - Elsevier
Due to the presence of protective mechanisms and blood-ocular barriers in the eye, drugs
aimed at treating posterior segment ophthalmic disorder have to be administrated mostly …

Effect of small extracellular vesicles derived from IL-10-overexpressing mesenchymal stem cells on experimental autoimmune uveitis

Y Li, X Ren, Z Zhang, Y Duan, H Li, S Chen… - Stem cell research & …, 2022 - Springer
Background Autoimmune uveitis is a sight-threatening intraocular inflammation mainly
caused by immune dysregulation. The development of safe and effective therapeutic …

[HTML][HTML] Progress in exosomes and their potential use in ocular diseases

SF Li, Y Han, F Wang, Y Su - International journal of …, 2020 - ncbi.nlm.nih.gov
Exosomes contain a variety of biological active substances such as proteins, miRNAs,
lncRNAs and lipids, and exosomes from different cells play different biological functions …