The uncertain brain: A co-ordinate based meta-analysis of the neural signatures supporting uncertainty during different contexts

J Morriss, M Gell, CM van Reekum - Neuroscience & Biobehavioral …, 2019 - Elsevier
Uncertainty is often inevitable in everyday life and can be both stressful and exciting. Given
its relevance to psychopathology and wellbeing, recent research has begun to address the …

Anxiety and the neurobiology of temporally uncertain threat anticipation

J Hur, JF Smith, KA DeYoung… - Journal of …, 2020 - Soc Neuroscience
When extreme, anxiety—a state of distress and arousal prototypically evoked by uncertain
danger—can be debilitating. Uncertain anticipation is a shared feature of situations that elicit …

Why am I unsure? Internal and external attributions of uncertainty dissociated by fMRI

KG Volz, RI Schubotz, DY Von Cramon - Neuroimage, 2004 - Elsevier
Behavioral evidence suggests that the perceived reason of uncertainty causes different
coping strategies to be implemented, particularly frequency ratings with externally attributed …

[HTML][HTML] Transdiagnostic computations of uncertainty: towards a new lens on intolerance of uncertainty

TR Sandhu, B Xiao, RP Lawson - Neuroscience & Biobehavioral Reviews, 2023 - Elsevier
People radically differ in how they cope with uncertainty. Clinical researchers describe a
dispositional characteristic known as “intolerance of uncertainty”, a tendency to find …

[HTML][HTML] Uncertainty and cognitive control

F Mushtaq, AR Bland, A Schaefer - Frontiers in psychology, 2011 - frontiersin.org
A growing trend of neuroimaging, behavioral, and computational research has investigated
the topic of outcome uncertainty in decision-making. Although evidence to date indicates …

Intolerance of uncertainty correlates with insula activation during affective ambiguity

A Simmons, SC Matthews, MP Paulus, MB Stein - Neuroscience letters, 2008 - Elsevier
Intolerance of uncertainty (IU), or the increased affective response to situations with
uncertain outcomes, is an important component process of anxiety disorders. Increased IU is …

[HTML][HTML] Intolerance of uncertainty is associated with heightened responding in the prefrontal cortex during cue-signalled uncertainty of threat

J Morriss, T Bell, N Biagi, T Johnstone… - Cognitive, Affective, & …, 2021 - Springer
Heightened responding to uncertain threat is considered a hallmark of anxiety disorder
pathology. We sought to determine whether individual differences in self-reported …

Neural correlates of intolerance of uncertainty in clinical disorders

M Wever, P Smeets… - The Journal of …, 2015 - Am Neuropsych Assoc
Intolerance of uncertainty is a key contributor to anxiety-related disorders. Recent studies
highlight its importance in other clinical disorders. The link between its clinical presentation …

[HTML][HTML] Intolerance of uncertainty and insula activation during uncertain reward

SM Gorka, BD Nelson, KL Phan… - Cognitive, affective, & …, 2016 - Springer
Individuals with high intolerance of uncertainty (IU) have been shown to exhibit abnormal
threat responding, which may be mediated by hyperactive anterior insula (aINS) response to …

The functional roles of the amygdala and prefrontal cortex in processing uncertainty

O FeldmanHall, P Glimcher, AL Baker… - Journal of Cognitive …, 2019 - direct.mit.edu
Decisions under uncertainty distinguish between those made under risk (known
probabilities) and those made under ambiguity (unknown probabilities). Despite widespread …