[HTML][HTML] LEM domain containing 1 promotes thyroid cancer cell proliferation and migration by activating the Wnt/β‑catenin signaling pathway and epithelial …
M Xu, B Lin, D Zheng, J Wen, W Hu, C Li… - Oncology …, 2021 - spandidos-publications.com
Thyroid cancer (TC) is the most common type of endocrine malignancy in humans, and its
relative incidence has increased continuously in recent years. However, the primary …
relative incidence has increased continuously in recent years. However, the primary …
Elevation of LEM Domain Containing 1 Predicts Poor Prognosis of NSCLC Patients and Triggers Malignant Stemness and Invasion of NSCLC Cells by Stimulating …
L Li, P Zhang - Current Molecular Medicine, 2024 - ingentaconnect.com
Background: Non-small cell lung cancer (NSCLC) is a leading cause of cancer-related
death globally. LEM domain containing 1 (LEMD1) function has been identified in several …
death globally. LEM domain containing 1 (LEMD1) function has been identified in several …
LEM domain containing 1 promotes pancreatic cancer growth and metastasis by p53 and mTORC1 signaling pathway
X Cao, N Yao, Z Zhao, Y Fu, Y Hu, P Zhu, W Shi… - …, 2022 - Taylor & Francis
Pancreatic cancer (PC) is a common type of malignancy originating from the epithelium of
the pancreatic duct, with the most lethal feature and worst prognosis. LEM domain …
the pancreatic duct, with the most lethal feature and worst prognosis. LEM domain …
[HTML][HTML] Collective analysis of the expression and prognosis for LEM-domain proteins in prostate cancer
T He, Y Zhang, X Li, C Liu, G Zhu, X Yin… - World Journal of …, 2022 - Springer
Background Mammalian LEM-domain proteins (LEMs) are encoded by seven genes,
including LAP2, EMD, LEMD1, LEMD2, LEMD3, ANKLE1, and ANKLE2. Though some …
including LAP2, EMD, LEMD1, LEMD2, LEMD3, ANKLE1, and ANKLE2. Though some …
LEM domain containing 1 promotes proliferation via activating the PI3K/Akt signaling pathway in gastric cancer
Q Li, Y Ge, X Chen, L Wang, Y Xia, Z Xu… - Journal of Cellular …, 2019 - Wiley Online Library
Gastric cancer (GC) is one of the most common cancers worldwide and has especially high
morbidity and mortality in China. LEM domain containing 1 (LEMD1), an important cancer …
morbidity and mortality in China. LEM domain containing 1 (LEMD1), an important cancer …
[HTML][HTML] Long noncoding RNA LEMD1-AS1 increases LEMD1 expression and activates PI3K-AKT pathway to promote metastasis in oral squamous cell carcinoma
Z Li, J Wang, J Wu, N Li, C Jiang - BioMed Research International, 2022 - hindawi.com
Background. The survival rate of oral squamous cell carcinoma (OSCC) is only 50% due to a
high incidence of metastasis. Long noncoding RNAs (lncRNAs) play a crucial role in OSCC …
high incidence of metastasis. Long noncoding RNAs (lncRNAs) play a crucial role in OSCC …
[HTML][HTML] Functional analysis of ESM1 by shRNA-mediated knockdown of its expression in papillary thyroid cancer cells
L Xie, L He, W Zhang, H Wang - Plos one, 2024 - journals.plos.org
Objective Endothelial specific molecule-1 (ESM1) is implicated as an oncogene in multiple
human cancers. However, the function of ESM1 in papillary thyroid cancer (PTC) is not well …
human cancers. However, the function of ESM1 in papillary thyroid cancer (PTC) is not well …
[HTML][HTML] A LETM2-regulated PI3K-Akt signaling Axis reveals a prognostic and therapeutic target in pancreatic cancer
S Zhou, Z Zhong, Y Lu, Y Li, H Yao, Y Zhao, T Guo… - Cancers, 2022 - mdpi.com
Simple Summary LEMT2 was a newly discovered protein-encoding gene with little cancer
research and an unclear mechanism. This study aimed to illustrate LETM2 as the crucial …
research and an unclear mechanism. This study aimed to illustrate LETM2 as the crucial …
[HTML][HTML] AEBP1 promotes papillary thyroid cancer progression by activating BMP4 signaling
G Ju, T Xing, M Xu, X Zhang, Y Sun, Z Mu, D Sun… - Neoplasia, 2024 - Elsevier
Papillary thyroid cancer (PTC) is the most prevalent endocrine cancer worldwide.
Approximately 30% of PTC patients will progress into the advanced or metastatic stage and …
Approximately 30% of PTC patients will progress into the advanced or metastatic stage and …
LEMD1-AS1 suppresses ovarian cancer progression through regulating miR-183-5p/TP53 axis
R Guo, Y Qin - OncoTargets and therapy, 2020 - Taylor & Francis
Background/Aims Long noncoding RNAs (lncRNAs) play a critical role in tumorigenesis and
progression of ovarian cancer (OC). This study focused on the function and potential …
progression of ovarian cancer (OC). This study focused on the function and potential …
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