The role of mitochondrial function in health and disease has become increasingly
recognized, particularly in the last two decades. Mitochondrial dysfunction as well as …

Since the first mitochondrial dysfunction was described in the 1960s, the medicine has
advanced in its understanding the role mitochondria play in health, disease, and aging. A …

Mitochondrial function is fundamental to metabolic homeostasis. In addition to converting the
nutrient flux into the energy molecule ATP, the mitochondria generate intermediates for …

Mitochondria are subcellular organelles evolved by endosymbiosis of bacteria with
eukaryotic cells characteristics. They are the main source of ATP in the cell and play a …

Mitochondria are the powerhouses of the cell and are involved in essential functions of the
cell, including ATP production, intracellular Ca 2+ regulation, reactive oxygen species …

Mitochondria are of great relevance to health, and their dysregulation is associated with
major chronic diseases. Research on mitochondria—156 brand new publications from 2019 …

Herein we trace links between biochemical pathways, pathogenesis, and metabolic
diseases to set the stage for new therapeutic advances. Cellular and acellular …

Mitochondria play a key role in both health and disease. Their function is not limited to
energy production but serves multiple mechanisms varying from iron and calcium …

Mitochondrial damage is implicated as a major contributing factor for a number of
noncommunicable chronic diseases such as cardiovascular diseases, cancer, obesity, and …

Mitochondria are well known as organelles responsible for the maintenance of cellular
bioenergetics through the production of ATP. Although oxidative phosphorylation may be …