'Real‐life'effectiveness studies of omalizumab in adult patients with severe allergic asthma: systematic review
I Abraham, A Alhossan, CS Lee, H Kutbi… - Allergy, 2016 - Wiley Online Library
Abstract We reviewed 24 'real‐life'effectiveness studies of omalizumab in the treatment of
severe allergic asthma that included 4117 unique patients from 32 countries with significant …
severe allergic asthma that included 4117 unique patients from 32 countries with significant …
“Real-life” effectiveness studies of omalizumab in adult patients with severe allergic asthma: meta-analysis
A Alhossan, CS Lee, K MacDonald… - The Journal of Allergy and …, 2017 - Elsevier
Background After the approval of omalizumab for severe allergic asthma, a total of 25
studies have evaluated the effectiveness of omalizumab under “real-life” conditions of …
studies have evaluated the effectiveness of omalizumab under “real-life” conditions of …
Real-world effectiveness of omalizumab in severe allergic asthma: a meta-analysis of observational studies
J Bousquet, M Humbert, PG Gibson, K Kostikas… - The Journal of Allergy …, 2021 - Elsevier
Background Assessment of clinical outcomes in the real-world corroborates findings from
randomized controlled trials (RCTs). Objective This meta-analysis evaluated real-world data …
randomized controlled trials (RCTs). Objective This meta-analysis evaluated real-world data …
[HTML][HTML] The eXpeRience registry: the 'real-world'effectiveness of omalizumab in allergic asthma
GJ Braunstahl, CW Chen, R Maykut, P Georgiou… - Respiratory …, 2013 - Elsevier
Omalizumab has demonstrated therapeutic benefits in controlled clinical trials. Evaluation of
outcomes in real-world clinical practice is needed to provide a complete understanding of …
outcomes in real-world clinical practice is needed to provide a complete understanding of …
Short-and long-term real-world effectiveness of omalizumab in severe allergic asthma: systematic review of 42 studies published 2008-2018
Introduction: Omalizumab is a recombinant monoclonal anti-IgE antibody approved in the
US as add-on treatment in moderate-to-severe allergic asthma (in severe allergic asthma …
US as add-on treatment in moderate-to-severe allergic asthma (in severe allergic asthma …
Omalizumab for severe allergic asthma in clinical trials and real-life studies: what we know and what we should address
M Caminati, G Senna, M Guerriero, AR Dama… - Pulmonary …, 2015 - Elsevier
Randomized clinical trials (RCTs) are the gold standard for the assessment of any
therapeutic intervention. Real-life (RL) studies are needed to verify the provided results …
therapeutic intervention. Real-life (RL) studies are needed to verify the provided results …
Omalizumab: a review of its use in patients with severe persistent allergic asthma
K McKeage - Drugs, 2013 - Springer
Omalizumab (Xolair®) is a subcutaneously administered monoclonal antibody that targets
circulating free IgE and prevents its interaction with the high-affinity IgE receptor (FCεRI) …
circulating free IgE and prevents its interaction with the high-affinity IgE receptor (FCεRI) …
Clinical and pharmacoeconomic aspects of omalizumab: a 4-year follow-up
F Menzella, N Facciolongo, R Piro… - Therapeutic …, 2012 - journals.sagepub.com
Objectives: The aim of this study was to assess the stability of the effectiveness of
omalizumab as add-on treatment in 11 patients with severe persistent allergic asthma …
omalizumab as add-on treatment in 11 patients with severe persistent allergic asthma …
[HTML][HTML] Longterm clinical outcomes of omalizumab therapy in severe allergic asthma: study of efficacy and safety
AH Mansur, S Srivastava, V Mitchell, J Sullivan… - Respiratory …, 2017 - Elsevier
Omalizumab has been shown to be an effective add-on therapy for patients with
uncontrolled severe persistent allergic asthma. There has been a steady accumulation of …
uncontrolled severe persistent allergic asthma. There has been a steady accumulation of …
[HTML][HTML] Predicting and evaluating response to omalizumab in patients with severe allergic asthma
BACKGROUND: Omalizumab is a monoclonal antibody indicated for treatment of severe
persistent allergic asthma inadequately controlled despite optimal controller therapy. We …
persistent allergic asthma inadequately controlled despite optimal controller therapy. We …