hydroxy-2-nonenal (HNE) is an amazing reactive compound, originating from lipid
peroxidation within cells but also in food and considered as a “second messenger” of …

4-hydroxy-2, 3-trans-nonenal (C9H16O2), also known as 4-hydroxy-2E-nonenal (C9H16O2;
HNE) is an α, β-unsaturated hydroxyalkenal. HNE is a major aldehyde, formed in the …

While reactive oxygen species (ROS) gain their carcinogenic effects by DNA mutations, if
generated in the vicinity of genome, lipid peroxidation products, notably 4-hydroxynonenal …

Due to the cytotoxicity of 4-hydroxynonenal (HNE), and to the fact that this major product of
lipid peroxidation is a rather long-living compound compared with reactive oxygen species …

4-Hydroxy-2, 3-nonenal (HNE) is a biologically active aldehydic end product of oxidative
decomposition of a-3 and u-6 polyunsaturated fatty acids of membrane phospholipids, a …

Significance: Oxidative stress provokes the peroxidation of polyunsaturated fatty acids in
cellular membranes, leading to the formation of aldheydes that, due to their high chemical …

Polyunsaturated fatty acids are susceptible to peroxidation and they yield various
degradation products, including the main α, β-unsaturated hydroxyalkenal, 4-hydroxy-2, 3 …

Hydroxynonenal (HNE) is a cytotoxic and genotoxic lipid oxidation secondary product which
is formed endogenously upon peroxidation of cellular n-6 fatty acids. However, it can also be …

Hydroxy-trans-2-nonenal (HNE), an α, β-unsaturated aldehyde generated endogenously by
the radical-mediated peroxidation of ω-6 polyunsaturated fatty acids, is a bioactive molecule …

Reacytive Oxygen Species (ROS) have long been considered to be involved in the initiation,
progression and metastasis of cancer. However, accumulating evidence points to the …