l-Carnitine (LC) is a naturally occurring quaternary ammonium compound endogenous in all
mammalian species and is a vital cofactor for the mitochondrial oxidation of fatty acids. Fatty …

l-carnitine is present in mammalian cells as free carnitine and acylcarnitines. The
acylcarnitine profile has been shown to be useful in identifying inborn errors of metabolism …

Abstract l-Carnitine functions to transport long chain fatty acyl-CoAs into the mitochondria for
degradation by β-oxidation. Treatment with l-carnitine can ameliorate metabolic imbalances …

In recent years increasing evidence has emerged suggesting that oxidative stress is
involved in the pathophysiology of a number of inherited metabolic disorders. However the …

Carnitine status in humans is reported to vary according to body composition, gender, and
diet. Plasma carnitine concentration positively correlates with the dietary intake of carnitine …

L-Carnitine (levocarnitine) is a naturally occurring compound found in all mammalian
species. The most important biological function of L-carnitine is in the transport of fatty acids …

Carnitine deficiency syndromes manifest as metabolic encephalopathy, lipid storage
myopathy, or cardiomyopathy. Impairment of long-chain fatty acid metabolism and failure of …

The objective of this article is to review primary and secondary causes of carnitine
deficiency, emphasizing recent advances in our knowledge of fatty acid oxidation. It is now …

Background: Current therapy of neurological disorders has several limitations. Although a
high number of drugs are clinically available, several subjects do not achieve full …

Carnitine Biosynthesis, Metabolism, and Functions contains the proceedings of the Virginia
Lazenby O'Hara Biochemistry Symposium held in Dallas, Texas, from March 31 to April 1 …