Importance The results of the American College of Surgeons Oncology Group Z0011
(ACOSOG Z0011) trial were first reported in 2005 with a median follow-up of 6.3 years …

Context Sentinel lymph node dissection (SLND) accurately identifies nodal metastasis of
early breast cancer, but it is not clear whether further nodal dissection affects survival …

Background Trials evaluating the omission of completion axillary-lymph-node dissection in
patients with clinically node-negative breast cancer and sentinel-lymph-node metastases …

Background The role of axillary lymph node dissection (ALND) has increasingly been called
into question among patients with positive sentinel lymph nodes. Two recent trials have …

Purpose Patients with breast cancer metastasis to the sentinel lymph nodes (SLNs)
generally undergo completion axillary lymph node dissection (cALND), either concurrently …

Methods: ACOSOG Z0011 prospectively examined overall survival of patients with SLN
metastases undergoing breast-conserving therapy randomized to undergo ALND after …

Importance Recent data from clinical trials have challenged traditional thinking about axillary
surgery in patients with breast cancer. Objectives To summarize evidence regarding the role …

CRA506 Background: Sentinel node biopsy (SNB) eliminates the need for axillary dissection
(ALND) in patients whose sentinel node (SN) is tumor-free. However, completion ALND …

BACKGROUND: The Z0011-study, a landmark randomised controlled trial (RCT) challenged
the benefits of complete axillary lymph node dissection (ALND) compared with sentinel …

Background We previously reported the 5-year results of the phase 3 IBCSG 23-01 trial
comparing disease-free survival in patients with breast cancer with one or more …