Reprogramming bacterial protein organelles as a nanoreactor for hydrogen production
T Li, Q Jiang, J Huang, CM Aitchison, F Huang… - Nature …, 2020 - nature.com
Compartmentalization is a ubiquitous building principle in cells, which permits segregation
of biological elements and reactions. The carboxysome is a specialized bacterial organelle …
of biological elements and reactions. The carboxysome is a specialized bacterial organelle …
Self-assembling biomolecular catalysts for hydrogen production
The chemistry of highly evolved protein-based compartments has inspired the design of new
catalytically active materials that self-assemble from biological components. A frontier of this …
catalytically active materials that self-assemble from biological components. A frontier of this …
Synthetic engineering of a new biocatalyst encapsulating [NiFe]-hydrogenases for enhanced hydrogen production
Q Jiang, T Li, J Yang, CM Aitchison, J Huang… - Journal of Materials …, 2023 - pubs.rsc.org
Hydrogenases are microbial metalloenzymes capable of catalyzing the reversible
interconversion between molecular hydrogen and protons with high efficiency, and have …
interconversion between molecular hydrogen and protons with high efficiency, and have …
Engineering bacterial microcompartment shells: chimeric shell proteins and chimeric carboxysome shells
Bacterial microcompartments (BMCs) are self-assembling organelles composed entirely of
protein. Depending on the enzymes they encapsulate, BMCs function in either inorganic …
protein. Depending on the enzymes they encapsulate, BMCs function in either inorganic …
Decoding the absolute stoichiometric composition and structural plasticity of α-carboxysomes
Y Sun, VM Harman, JR Johnson, PJ Brownridge… - MBio, 2022 - Am Soc Microbiol
Carboxysomes are anabolic bacterial microcompartments that play an essential role in
carbon fixation in cyanobacteria and some chemoautotrophs. This self-assembling …
carbon fixation in cyanobacteria and some chemoautotrophs. This self-assembling …
The bacterial carbon-fixing organelle is formed by shell envelopment of preassembled cargo
Background Cyanobacteria play a significant role in the global carbon cycle. In
Synechococcus elongatus, the carbon-fixing enzyme ribulose-1, 5-bisphosphate …
Synechococcus elongatus, the carbon-fixing enzyme ribulose-1, 5-bisphosphate …
Incorporation of functional Rubisco activases into engineered carboxysomes to enhance carbon fixation
T Chen, Y Fang, Q Jiang, GF Dykes, Y Lin… - ACS Synthetic …, 2021 - ACS Publications
The carboxysome is a versatile paradigm of prokaryotic organelles and is a proteinaceous
self-assembling microcompartment that plays essential roles in carbon fixation in all …
self-assembling microcompartment that plays essential roles in carbon fixation in all …
New discoveries expand possibilities for carboxysome engineering
JS Borden, DF Savage - Current Opinion in Microbiology, 2021 - Elsevier
Carboxysomes are CO 2-fixing protein compartments present in all cyanobacteria and some
proteobacteria. These structures are attractive candidates for carbon assimilation …
proteobacteria. These structures are attractive candidates for carbon assimilation …
[HTML][HTML] Biogenesis of a bacterial organelle: the carboxysome assembly pathway
The carboxysome is a protein-based organelle for carbon fixation in cyanobacteria,
keystone organisms in the global carbon cycle. It is composed of thousands of subunits …
keystone organisms in the global carbon cycle. It is composed of thousands of subunits …
Halothiobacillus neapolitanus Carboxysomes Sequester Heterologous and Chimeric RubisCO Species
Background The carboxysome is a bacterial microcompartment that consists of a polyhedral
protein shell filled with r ib u lose 1, 5-bis phosphate c arboxylase/o xygenase (RubisCO) …
protein shell filled with r ib u lose 1, 5-bis phosphate c arboxylase/o xygenase (RubisCO) …