The resistance of pathogenic microbes to currently available antimicrobial agents has been
considered a global alarming concern. Hence, close attention should be paid to the …

Abstract New 6, 7-dimethylquinoxalin-2 (1H)-one and hydrazineylidene thiazol-4-one
derivatives were synthesized, and evaluated for their in vitro antimicrobial activity. The …

Herein, we report the synthesis and in vitro antimicrobial evaluation of novel quinoline
derivatives as DNA gyrase inhibitors. The preliminary antimicrobial activity was assessed …

Synthesis and molecular validation of 6-substituted-2-(3-phenoxyphenyl)-4-phenylquinoline
derivatives (4a-h) as antibacterial/DNA gyrase inhibitors reported. Primarily, 6-substituted-2 …

A new series of coumarin-6-sulfonamide derivatives 3–16 have been synthesized via simple
and convenient coupling reaction of coumarin-6-sulfonyl chloride with different sulfa drugs …

The rapidly increasing rate of antibiotic resistance is of great concern. Approximately two
million deaths result annually from bacterial infections worldwide. Therefore, there is a …

The (E)-N′-(substituted-benzylidene)-2-(7-fluoro-2-methoxyquinolin-8-yl) acetohydrazide-
hydrazone derivatives reported in this manuscript represent a new series of antibacterial …

Antimicrobial resistance is one of the greatest challenges facing the world today. In the
United States alone, it is responsible for the death of more than 20,000 people each year …

Abstract A novel series of [1, 2, 4] triazolo [4, 3-a] quinoxaline derivatives of different
heteroaromatization members were synthesized. The newly synthesized molecules were …

New antibacterial drugs are urgently needed to tackle the rapid rise in multi-drug resistant
bacteria. DNA gyrase is a validated target for the development of new antibacterial drugs …